"Our data suggest immunity to Dengue virus only modestly shapes breadth and magnitude of enduring Zika virus antibody responses". New paper from Harris @NatureComms:https://www.nature.com/articles/s41467-019-08845-3 …
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So that big hullabaloo about the recent Science paper was over-interpreted? I need to read them closely to compare, but from all the press releases, it sounded like dengue protected against Zika.
I honestly have no idea... Very confusing science at the moment, but I'm glad so many great people are looking into it - and by now I basically ignore all the mouse/in vitro studies.
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Agreed but there is value to in vitro studies, depending on the question.
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Totally agree - but in the case of DENV <> ZIKV immunity interactions, in vitro systems (and mouse models) are too simplistic and don't capture (or reflect) a much more complex immune response.
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