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Prikvačeni tweet
A lot of talk about sequencing and tracking the
#2019nCoV epidemic. If you're interested in learning how this all works, we recently wrote a large(ish) review on genomic epidemiology. Link: https://www.ncbi.nlm.nih.gov/pubmed/30546099 Get it here: https://andersen-lab.com/papers/grubaugh-et-al-nat-microbiol-2019/ …pic.twitter.com/6POeuUeKkq
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This is a pretty interesting tidbit from the most recent
@WHO report on#2019nCoV. Not surprising - kinda sad, but definitely necessary. The R0 of misinformation is massively higher than the R0 of the virus. https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200202-sitrep-13-ncov-v3.pdf?sfvrsn=195f4010_2 …pic.twitter.com/jq7nJUxnvu
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Note, the scientific response has been absolutely stellar in my opinion, so it's important not to mix it all up.
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Two good articles describing some of the critical issues that 'hampered' the early response to
#2019nCoV. https://www.nytimes.com/2020/02/01/world/asia/china-coronavirus.html?smid=tw-nytimesscience&smtyp=cur …https://www.washingtonpost.com/world/2020/02/01/early-missteps-state-secrecy-china-likely-allowed-coronavirus-spread-farther-faster/ …Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Kristian G. Andersen proslijedio/la je TweetHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi
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So in case you were wondering - the
@biorxivpreprint is far from broken and it's transforming our ability to accelerate scientific findings - some
, many
. Just take a look at all of the *amazing* science already published on a virus we didn't know existed a month ago. 

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And finally these two describing how this thing is spreading. https://www.biorxiv.org/content/10.1101/2020.01.23.917351v1 … https://www.biorxiv.org/content/10.1101/2020.01.25.919787v1 …pic.twitter.com/1kAGui1E1T
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Oh yeah, ACE2 really IS the receptor - same as SARS-CoV. Turns out TMPRSS2 is involved too. https://www.biorxiv.org/content/10.1101/2020.01.31.929042v1 …pic.twitter.com/OG1UkdKIK1
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So how long does it take to figure out what the receptor is? Hmmm, about a week... Yikes. https://www.biorxiv.org/content/10.1101/2020.01.22.915660v1 …pic.twitter.com/D2URIgIHxP
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Oh hey, these folks sequenced and released the first sequence allowing for the development of diagnostics. https://www.biorxiv.org/content/10.1101/2020.01.24.919183v1 …pic.twitter.com/efLi0FQxSl
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This one describing a bunch of things about the virus and outbreak. https://www.biorxiv.org/content/10.1101/2020.01.22.914952v2 …pic.twitter.com/so5hBHa07j
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While the Twittersphere has been freaking out about snake flu and HIV-corona mutant viruses

, if you're interested in learning more about #2019nCoV may I suggest you instead read these six *amazing*@biorxivpreprint's. Published only in the last week!
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Kristian G. Andersen proslijedio/la je Tweet
These short inserts do indeed exist in
#nCoV2019 relative to its closest sequenced relative (BetaCoV/bat/Yunnan/RaTG13/2013, seen here https://nextstrain.org/groups/blab/sars-like-cov …). However, a simple BLAST of such short sequences shows match to a huge variety of organisms. No reason to conclude HIV. https://twitter.com/biorxivpreprint/status/1223245639296978951 …pic.twitter.com/mUfxwB6GsP
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Clear evidence of asymptomatic transmission of
#2019nCoV outside China. This case report is pretty interesting and worth reading.https://www.nejm.org/doi/full/10.1056/NEJMc2001468 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
We also wrote a shorter version that was a little more targeted towards a clinical audience. Link: https://www.ncbi.nlm.nih.gov/pubmed/30728537 Get it here: https://andersen-lab.com/papers/ladner-et-al-nat-med-2019/ …pic.twitter.com/3NYWRFtcMZ
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For the modeling folks out there - is anybody looking at suitability for 2019-nCoV in addition to transport and the risk of imports? Several places in Africa would be at high risk for imports, but given climate differences, possibly not all that suitable for onward transmission?
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Kristian G. Andersen proslijedio/la je Tweet
First person-to-person transmission in the US isn't quite as alarming as it might sound at first. A woman who had been to Wuhan and got sick when she was back in Chicago passed the virus to her husband.
@ByLenaSun &@LennyMBernsteinhttps://www.washingtonpost.com/world/asia_pacific/china-coronavirus-live-updates/2020/01/30/1da6ea52-4302-11ea-b5fc-eefa848cde99_story.html …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Kristian G. Andersen proslijedio/la je TweetHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi
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Kristian G. Andersen proslijedio/la je Tweet
Very solid review of excessive extrapolation from murine models and other shortcomings in microbiome science. People will lose patience with the microbiome if these issues aren't addressed (they already are...), which will delay its clinical application:https://www.sciencedirect.com/science/article/pii/S009286741931387X …
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Kristian G. Andersen proslijedio/la je Tweet
#WuhanCoronavirus#nCoV2019 outbreak: 7811 confirmed cases with 7711 cases in China (excl. Hongkong, Macau and Tibet) and 100 cases in other countries (incl. 7 locally transmitted cases) as of 29 Jan per@WHO,@ProMED_mail,@FluTrackers and Chinese MOHpic.twitter.com/meYJYTOlCl
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