Medijski sadržaj
- Tweetovi
- Tweetovi i odgovori
- Medijski sadržaj, trenutna stranica.
-
Intriguingly, the connection to lateral habenula is potentiated both when tone and footshock are paired or unpaired.pic.twitter.com/BktT2SdOB1
Prikaži ovu nit -
Similarly, SYNPLA works on ex vivo slices of defense conditioned animals. When expressing myc-NRXN in auditory cortex and/or medial geniculate nucleus, we show that paired tone and footshock potentiate the connection to the lateral amygdala relative to controls.pic.twitter.com/3zHp4X1NZx
Prikaži ovu nit -
In the paper, we show that SYNPLA works in cultured neurons and hippocampal slice cultures. There we detect a much larger number of SYNPLA signals after chemically induced LTP than in control conditions or when LTP is blocked.pic.twitter.com/XxxhnijE2B
Prikaži ovu nit -
In SYNPLA we probe for endogenous GluA1 and the pathway-specifically expressed pre-synaptic myc-NRXN. We only get a SYNPLA signal if a synapse contains both GluA1 and myc-NRXN . Extra-synaptic GluA1 is too far away from the presynaptic partner to make a signal!pic.twitter.com/lipwzUVRvl
Prikaži ovu nit -
We do this by PLA. PLA is essentially a double antibody stain that results in a 1000x amplified signal only if the two proteins probed for are closer than 40nm to each other. This happens across the synaptic cleft.pic.twitter.com/BMFl674TVS
Prikaži ovu nit -
Are you mapping brain circuits by clearing and light sheet imaging, but have a hard time truely quantifying axonal projections? Check out Drew Friedmann's TrailMap (Luo Lab) now on biorxiv. Then you too can make awesome movies like this one!
@_Friedmann_ https://www.biorxiv.org/content/10.1101/812644v1 …pic.twitter.com/NObM9FJSND -
Want connectivity maps of your favourite model system? We used barcoding and DNA sequencing to map the mesoscale cortical connectome of individual mice in just single experiments. Work impossible without Longwen Huang and
@TonyZador. Feedback welcome! https://tinyurl.com/y8yjuazl pic.twitter.com/3pVnkf392DPrikaži ovu nit
Čini se da učitavanje traje već neko vrijeme.
Twitter je možda preopterećen ili ima kratkotrajnih poteškoća u radu. Pokušajte ponovno ili potražite dodatne informacije u odjeljku Status Twittera.