We have an open graduate student position at Dalhousie University (metabolismlab.com). Candidates interested in research focusing on bioactive lipids, energy metabolism and metabolic disorders are encouraged to apply! See linkedin.com/jobs/view/2588 for details.
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John Ussher
@JussherLab
Proud father, enthusiastic scientist, Red Wings Diehard, space lover, NFL addict and Game of Thrones Fanatic
Joined March 2015
John Ussher’s Tweets
In honour of the #RareDiseaseDay and #HeartMonth, I am very excited to share our manuscript (#preprint) on the role of the #KBGsyndrome risk gene Ankrd11 in heart development 1/11
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Ankrd11, a chromatin regulator and a KBG syndrome risk gene, is a critical regulator of cardiac neural crest cell biology and heart development #preprints researchsquare.com/article/rs-260
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Exercise at any time of the day is better than no exercise at all, but here Logan Pendergrast and I summarized the latest from our team #exercise
Morning exercise burns more body fat, mouse study shows theconversation.com/morning-exerci via
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7 years later- data from my PhD non clinical (heart perfusion) project finally was published! 🥳🤓❤️ On the interdependence of ketone body oxidation,glycogen content, glycolysis and energy metabolism in the heart
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G9a/GLP Targeting Ameliorates Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension pubmed.ncbi.nlm.nih.gov/36724371/
congrats and PAH research group of
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Our Department of is hiring! We seek tenure-track faculty who will study 🔥#inflammation🔥 in the #cardiovascular system, #muscle, #metabolism, #diabetes, #obesity, or #stress.
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Happy international women and girls in science day to all the women serving on the SHVM executive board and all of the talented women in the SHVM family #WomenAndGirlsInScience #WomenInSTEM #WomenInScience #SHVM
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@CircRes Feb 3rd current author @ArdehaliHossein has an earlier review on Getting to the "Heart" of Cardiac Disease by Decreasing #Mitochondrial #Iron. Check it out at ahajrnls.org/3lwl84c
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some very exciting news to share that received a fellowship from and we look forward to sharing his current work on developing new pharmaceutical agents that decrease #ketone #oxidation to promote #glucose_lowering in the future!
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Recruiting a PDF to do depression research in rats. Focus on sex-specific vulnerability. Training in Mol/cell bio, systems ephys, behavior provided. Experience with stereotactic rodent surgery is an asset. I have a great cross-cultural group, inclusive research envt. Please RT.
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New postdoc position available in my lab! We are looking for a passionate and creative researcher in cardio-metabolism. Please apply and/or RT!
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Come join me at ! Human Nutrition has TWO tenure track positions that just opened! ubc.wd10.myworkdayjobs.com/en-US/ubcfacul #AcademicTwitter
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The brave new world of mitochondrial endocrinology and intra- and extracellular communication #EndocrineReviews academic.oup.com/edrv/advance-a
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Our Review on ACE2: the SARS-CoV-2 Receptor at the heart of the COVID Pandemic: Great working with my friend and collaborator, Josef Penninger, and our wonderful trainees.
Angiotensin Converting Enzyme 2 - at the Heart of the COVID-19 pandemic
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I know I’m obviously biased but our lab is a great, fun environment and very diverse, and it isn’t science all day lots of time to discuss #GameofThrones #TheLastofUs #NFL and a whole bunch of other non-sciency (is that a real word?) stuff too!
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It’s been a while since I used Twitter for this, but our lab is looking to recruit a new #postdoc, if anyone is interested in studying either #cardiac or #skeletal_muscle #energy #metabolism in #obesity or #rare_genetic_diseases, please DM me and others please RT
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Because you all know she’ll see this, a MASSIVE CONGRATULATIONS to the legendary Dr Erin Mulvihill on her Project grant 🍻🎉🍻🍾 keep hurrying hard!!!
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Thrilled to share our latest findings on the potential of DG9-conjugated morpholino as a treatment for spinal muscular atrophy! Our study shows significant improvements in survival, SMN expression, and muscle function in a mouse model. insight.jci.org/articles/view/
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Skeletal muscle functions like an endocrine organ, producing and secreting myokines that exert their effects in either an autocrine, paracrine, or endocrine manner…
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After decades of confusion and many thousands of papers some real clarity is emerging as to how metformin actually works. Its key sire of action is the intestinal epithelial cell, into which it is selectively very concentrated. There, it impairs mitochondrial oxphos and
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Beautiful work from #judyhirst. As she predicted years ago, metformin is indeed a mitochondrial Complex 1 inhibitor. science.org/doi/10.1126/sc
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📣 Come be our new colleagues! 6 TT positions, both junior and senior. The LSI already has 85 fantastic labs and a beautiful range of research questions. Help us expand further. DM me with any questions.
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The LSI is launching a search for 6 diverse faculty members, across career stages, around the concept of Biological Resilience. lsi.ubc.ca/2023/01/27/six
Share widely!
@JimJohnsonSci @UBCmedicine @SBME_UBC @UBCcps @ZoologyUBC @UBCbiochemistry @UBCMicroImmuno @EJRideout
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Really cool recognizing areas of #Edmonton in episode 2 of and looking forward to seeing the rest of the season unfold !!!
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📣 Join us Monday, January 23, from 12-1 pm MT
ADI Member Dr. René Jacobs discusses how liver phospholipid metabolism impacts weight gain and development of #T2D
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In our latest issue: Michael Riddell and Anne Peters review #exercise in type 1 #diabetes (£) go.nature.com/3g3sF8l
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We are hiring! Research fellow position available in the Cellular & Molecular Cardiology lab at the University of Auckland, NZ. In collaboration with the Cardiac Research Consortium in Melbourne.
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Had a great time yesterday at the HF symposium. Heading to the airport back to Edmonton and hope it’s not another 8 years until I get to return to the great city of #Toronto again!!
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Getting ready to fly to #Toronto and looking forward to attending and speaking at the Heart Failure Symposium!
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GLP-1 and GIP are physiologically essential for suppression of #inflammation and pharmacologically suppress inflammation, actions potentially relevant to reduction of complications #T2D How and where do incretins instruct the immune system? nature.com/articles/s4157
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Leading from behind, on the sidelines, as the worlds major science powers continuously reinvest, is not a strategy for success. 🇨🇦 has the scientific talent, lets give them the oxygen and resources to compete and just watch how they will excel
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There is still time to alter course and make Canadian research globally competitive in #Budget2023 by doubling funds to the Tri-Councils and paying post-graduate students a living wage.
#CANFundScience #SupportOurScience @jyduclos @FP_Champagne @cafreeland
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We are recruiting (again)! If you are finishing up your degree and interested in studying T cell-mediated anti-tumor immunity and/or autoimmune disease from a metabolic lens, please get in touch by DM or email!
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Truly a labour of love that I’m so excited to share finally! Our manuscript in diving deeper into how hepatocyte derived DPP4 influences hepatic glucose production, liver disease progression and metabolism! 👏🏻
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Anyone who knows me well, knows I'm a HUGE #RedWings fan! I bring that same enthusiasm and dedication to my work, and I'm excited to discuss it at 's annual Heart Failure Symposium Dec 16-17. I hope you'll join me in person or online: tedrogersresearch.ca/symposium/ 👈👈
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Is Irisin truly a myokine and what's its role in bone? read my commentary in Diabetes!
Irisin: The Bony Builder Flexes Its Muscles
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Add 20 and 21 to the goal total now, just so cool to see and hoping #50goals for the season is possible!
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Interested in joining a reasonably competent, always curious group of scientists working on translating basic science to the clinic? The Drucker lab is looking for full time technical assistance. Cool projects, friendly people, tolerable supervisor 😎
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2 more goals today to take sole possession of 1st place!
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