Julia B.

@JuliaB_fitness

Vrijeme pridruživanja: travanj 2015.

Medijski sadržaj

  1. 27. sij
    Odgovor korisnicima i sljedećem broju korisnika:

    We just have to turn our bodies into natural /youth pharmacies/factories! Everything we need to be is likely already inside of us!

  2. 27. sij
    Odgovor korisnicima i sljedećem broju korisnika:

    Is an upstream regulator of the immune system? «The OSS (oxytocin-secreting system) can promote the development of thymus and bone marrow, perform immune surveillance, strengthen immune defense, and maintain immune homeostasis.»

  3. 22. sij
    Odgovor korisnicima

    Overview over lifespan extending effects in rodents by CR and various compounds: Only problem is that Michael Rose has calculated that even a lifetime of CR in humans will extend life by a couple of years at most (basically zero).

  4. 22. sij
    Odgovor korisnicima

    And according to this article, in a 1981 study extended lifespan (at least in some female mice) far more than anything else.

  5. 22. sij
    Odgovor korisnicima

    It has nothing to do with real . extends murine lifespan but has limited effects on aging «Our data indicated that the longevity effects of rapamycin are not associated with broad modulation of aging.»

  6. 22. sij
    Odgovor korisnicima

    And also (BFT) (an emerging supplement that seems to work via multiple mechanisms):

  7. 21. sij
    Odgovor korisnicima i sljedećem broju korisnika:

    Almost everything is likely tissue/context/biostatus dependent & it’s why «broad» pharmacological inhibitors etc never will work for «» in humans

  8. 20. sij
    Odgovor korisnicima i sljedećem broju korisnika:

    Supraphysiologic Administration of Induces and loss in Part by Upregulating :

  9. 18. sij
    Odgovor korisnicima

    Great question but the whole premise is wrong in the first place. The mTOR hypothesis in humans is basically dead and after this failed trial no one is going waste more money on it (which is probably fortunate.) The future is not «managing death/decline».

  10. 17. sij
    Odgovor korisnicima

    The most interesting properties of , plant compounds & also «» is their epigenetic properties (that’s only now starting to get elucidated), see for example this recent review:

  11. 16. sij
    Odgovor korisnicima i sljedećem broju korisnika:

    Well, that idea just isn’t aligned with reality. Diseased/aged people are *catabolic* (and increasingly so the sicker/older they are) NOT «anabolic» and basically all functions starts to decline very early.

  12. 14. sij
    Odgovor korisniku/ci

    Does senescence promote fitness in Caenorhabditis elegans by causing death? (David Gems)

  13. 14. sij
    Odgovor korisniku/ci

    «The existence of different causal explanations at different stages of the disease: identifying these different explanations, and determining if they are connected or not, will benefit researchers.»

  14. 14. sij
    Odgovor korisnicima

    "Where a probiotic supplement may boast a few strains and 25 billion live organisms per dose, a modest serve of just 25 grams of could provide the same total microbes across a diverse population which may include over 150 genera."

  15. 12. sij
    Odgovor korisnicima i sljedećem broju korisnika:

    Ok, but be careful and see this: administration is not a valid therapeutic strategy for every case of mitochondrial disease

  16. 12. sij
    Odgovor korisnicima i sljedećem broju korisnika:

    «Similar to the melody from an accordion, the output of signaling is shaped by the integration of multiple input parameters.»

  17. 11. sij
    Odgovor korisnicima i sljedećem broju korisnika:

    is probably a far more effective tool than or will ever be (but the question is if Met/Rapa will diminish the benefits of exercise). Antioxidant and Adaptative Response Mediated by during Physical Exercise

  18. 3. sij
    Odgovor korisniku/ci

    «In conclusion, dietary fibers can be considered key ancestral compounds that preserve gut ecology, especially regulating macronutrients and host physiology.»

  19. 25. pro 2019.
    Odgovor korisnicima

    It’s complex but according to the mouse model in this paper it seems like the earliest signs of may occur in a part of this brain circuit: It seems by delivering a designer drug that inhibited neuronal «overactivity» there it reduced Aβ

  20. 25. pro 2019.
    Odgovor korisniku/ci

    But might it be ? Differential regional decline in dopamine receptor availability across adulthood: Linear and nonlinear effects of age. 2019

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