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Prikvačeni tweet
With its ability to store information, replicate & evolve, biology is one of the most advanced technologies on earth. And now biology is becoming programmable. My take on what is powering our ability to read, write + execute programs in biology
https://a16z.com/2019/12/02/programming-biology-read-write-execute/ …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Jorge Conde proslijedio/la je Tweet
Accurate early detection blood test for cancer is going to be one of the most fundamental breakthroughs of our generation. Within a few years, we will detect cancer at the earliest points when it can be cured: https://www.cnbc.com/amp/2020/02/01/detecting-cancer-through-liquid-biopsies-freenome-grail-thrive.html …
@freenome@MichaelPellini@AmericanCancerPrikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
“Not Spicy = Not As Good” is a hill I’m willing to die on.https://twitter.com/amandamull/status/1222961608785305606 …
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#girldad (and dad to a Spider-Verse Spider-Man)pic.twitter.com/qDmzIKD4Mt
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“Don’t ask yourself what the world needs. Ask yourself what makes you come alive, and go do that, because what the world needs is people who have come alive.” — Howard Thurman (h/t
@AspenInstitute@AspenAGLN)Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Jorge Conde proslijedio/la je Tweet
"It's easier to hold your principles 100 percent of the time than it is to hold them 98 percent of the time." -- Clayton Christensen, giant of enterprise, RIP
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Jorge Conde proslijedio/la je Tweet
5-year predictions 1. Active learning in biology - confluence of design (ML), build (large-scale dna synth/edit), and test (multiplexed assays) allows massive scale for exploring new function. Will require programmatic ways to explore that space. Expmnts no longer limiting. [1/n]https://twitter.com/AGoulburn/status/1220038803181752320 …
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Should tech stick to tech; biotech to biotech? It’s hard to stay in your lane when roads merge. Some things are best for traditional tech/biotech; others, bio’s sweet spot. And tech, biotech + bio will work together to bridge from the old world + build the new. See you at
#JPM21!Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Silicon Valley,
@Genentech’s birthplace, is an important hub for both traditional biotech + next-gen bio companies. And a thriving ecosystem of seed, early- + late-stage bio investors has emerged. Like bio founders, these investors are multidisciplinary too.Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
‘Reimbursement risk’ (aka value proposition risk) is changing too. As programmable medicines become more sophisticated, they offer potential cures—saving lives + avoiding downstream costs. We need new models to fairly distribute costs + benefits over many years.
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‘Regulatory risk’ (aka science risk) is changing as engineered bio pursues applications where iteration can reduce risk: ie optimize genome editors to repair known disease-causing errors; 1st clinical applications ex vivo (outside of body) that can be QC’d before they’re infused.
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Bio companies are a hybrid between traditional tech + biotech. They merge siloed disciplines—and build cultures of relentless iteration + continuous improvement. Entrepreneurs unhappy w/ status quo seek to remake the entire industry (ie
@EQRxINC). Naturally, skeptics abound.Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
We’re in a bio revolution. Innovation cycles are accelerating + compounding. Advances (ie DNA seq, CRISPR) rapidly adopted. Engineered bio creates generations that build on each other, like versions of software. Modular components can be remixed + reused (ie CAR T 2.0)
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True platforms are coming to bio, built on computational/engineering foundations that give meaningful tech-enabled knowledge or capability edge. One example: AI. Excitement can crossover into hype, but AI is helping take some guesswork out of clinical diagnosis + drug discovery.
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Traditional biotech VCs created a generation of transformational biotech companies. But a new breed of bio founder wants to take the reins: they’re domain experts; many are best positioned to drive their own innovations forward as CEO. Bio VCs need to catalyze rather than create.
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Reflecting on
#JPM20, I’m struck by a sea change in healthcare. Everything is on the table: questioning old assumptions, sparking new debates. As traditional tech + biotech merge into “bio”, we need to revisit some outdated mindsets for this new world
https://a16z.com/2020/01/11/16-bio-myths-misconceptions/ …Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
Good on you,
@JohnsHopkins. Thank you, Pres Ron Daniels. And this undoubtedly wouldn’t be possible without@MikeBloomberg—his incredible acts of generosity have transformed the lives of generations of JHU students. Johns Hopkins had an indelible impact on my life and career. https://twitter.com/TheAtlantic/status/1218558188477452289 …pic.twitter.com/t3h8NRmoUN
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“If you lived here you’d be a home by now.”https://twitter.com/thisischristina/status/1217630903368933381 …
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If EQRx achieved even a fraction of their goal, it would still have an incredible impact on the industry, and most importantly, help patients.
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In fairness, it’s a thoughtful critique. But a bet is a cheap stunt. Anyone could bet every company on the planet that they won’t hit their 10-yr projections and would win every single time.
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