I fight infectious diseases. Opinions are solely my own & do not express the views of my employer or the US Government. #IDTwitter #HIVTwitter
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I’m thrilled to share the results of the J&J / Janssen one dose vaccine. Many ENSEMBLE sites and investigators, including me, worked on this for many months. Consistent with other vaccines - divergence of cases & hospitalizations after day 14 seen. https://www.fda.gov/media/146217/download …pic.twitter.com/ut1Wvu6N7D
Efficacy highlights: - 85% vs severe disease after 28d (often mild hypoxia as case definition) -100% against severe disease requiring hospitalization Again, a two dose regimen trial is underway to see if we can increase numbers further.
Transmission prevention 
Protection against asymptomatic infection = 74% efficacy
(seroconversion without prior symptoms, subgroup analysis)
Very promising for transmission prevention.
A one dose vaccine with limited cold chain reliance is a likely game changer for the USpic.twitter.com/o1nKFSbbVw
Let's get this on air...
I am so excited!!!! I hope this will let my siblings and young adult children be vaccinated sooner. Most of the people I love are 20-55 yo and generally healthy. But having worked in the COVID ICU, I know they are still at risk of severe lingering illness or even death.
This is great news for the world. Thank you so much for your hard work.
what are the adverse side effects? there seem to be many with the other two vaccines
Can you explain why this vaccine prevents transmission 74% please? Like dumb it down for me a bit so I can explain it to others.
Congratulations! This is great news for the world.
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