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Prikvačeni tweet
There is an amazing evolutionary biology paper out this week in Science: DNA fragility in the parallel evolution of pelvic reduction in stickleback fish http://science.sciencemag.org/content/363/6422/81 … Let’s look at what they did.pic.twitter.com/kigKik1ddu
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James Lingford proslijedio/la je Tweet
"A clearer understanding of genetic relationships of childhood maltreatment, incl particular abuse subtypes, with a range of phenotypes, may ultimately be useful in in developing targeted treatment and prevention strategies." Unethical and irresponsible.https://www.nature.com/articles/s41398-020-0706-0 …
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James Lingford proslijedio/la je Tweet
Based on the content of my mentions, I feel like I need to further debunk crazy
#nCoV2019 / HIV conspiracy preprint. This is a thread doing so. 1/9Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
James Lingford proslijedio/la je Tweet
I've been seeing this kind of response to my paper from would-be critics claiming I show 20% of the racial IQ gap is genetic and claiming it supports race science (and that I am a race scientist). While this criticism is obviously in bad faith I want to address any ambiguity herepic.twitter.com/jQonhvv6oU
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James Lingford proslijedio/la je Tweet
I've checked it because this claim that HIV inserts in
#nCoV2019 & not fortuitous is insane. So I aligned the sequences & those inserts are real. However I've blast those peptides & founds > 100 hits from various organisms. In my view#nCoV2019 - HIV link not ascertained. https://twitter.com/ARanganathan72/status/1223320879162986496 …Tweet je nedostupan.Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
James Lingford proslijedio/la je Tweet
The mere claim that such short inserts support nCoV origins "unlikely to be fortuitous in nature" [sic] is already highly suspect. This is a classic case of searching for lost keys only under a lamppost. A fearful world does not need to fuel conspiracy theories with bad analyses.https://twitter.com/SKonermann/status/1223344537772290048 …
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James Lingford proslijedio/la je Tweet
These short inserts do indeed exist in
#nCoV2019 relative to its closest sequenced relative (BetaCoV/bat/Yunnan/RaTG13/2013, seen here https://nextstrain.org/groups/blab/sars-like-cov …). However, a simple BLAST of such short sequences shows match to a huge variety of organisms. No reason to conclude HIV. https://twitter.com/biorxivpreprint/status/1223245639296978951 …pic.twitter.com/mUfxwB6GsP
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James Lingford proslijedio/la je Tweet
Please see the comments coming in from expert biologists like
@surt_lab explaining why these insertions are coincidence and highly unlikely to be from HIV https://www.biorxiv.org/content/10.1101/2020.01.30.927871v1#comment-4778838650 … https://twitter.com/ARanganathan72/status/1223320879162986496 …Tweet je nedostupan.Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
James Lingford proslijedio/la je Tweet
Considering Charles Murray's new book comes out tomorrow it's good timing that this little side-project I took on (in the middle of my comprehsensive exams!) just came out.https://osf.io/preprints/socarxiv/2qfkt/ …
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James Lingford proslijedio/la je Tweet
I wrote this, a selection of a couple of ideas from my new book
#HowToArgueWithARacist please share widely, there’s a storm coming...
https://www.theguardian.com/world/2020/jan/26/fight-racism-using-science-race-genetics-bigotry-african-americans-sport-linnaeus …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
James Lingford proslijedio/la je Tweet
I study genocide. It's been a theme in my academic endeavours for nearly 30 years. More accurately, I study the conditions in the lead up to genocide, be they cultural, social, political, economic, etc... 1/n
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Evolutionary biology educators & communicators used to deal with creationist myths & misconceptions. Now they have to deal with whatever the hell this hyper-adaptationist BS is. How times have changed.https://twitter.com/uberfeminist/status/1219535651445428225 …
2:03Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
James Lingford proslijedio/la je Tweet
Great to see our study on ligand flexibility
@ChemicalScience! We report how to dissect contributions from direct contacts and ligand flexibility to complex stability. Congrats to everyone involved@VU_Science +@AstraZeneca! https://pubs.rsc.org/en/content/articlelanding/2020/sc/c9sc04705k …#peptidomimetics@AdrianGlaspic.twitter.com/OvYQBnz42K
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James Lingford proslijedio/la je Tweet
Systematically mapping protein-drug interactions in vivo could greatly expedite and improve drug discovery. Together with Cellzome we adapted TPP to the in vivo setting and find organ-specific drug target interactions and protein interaction states.https://www.nature.com/articles/s41587-019-0388-4 …
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Dynamics of oligomer populations formed during the aggregation of Alzheimer’s Aβ42 peptide https://www.biorxiv.org/content/10.1101/2020.01.08.897488v1 … Beautiful work here from
@KnowlesLabCambpic.twitter.com/n9ENFykzeN
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Scientists should approach empirical hypotheses responsibly w/ a social & historical awareness. To hypothesise "some races may have a genetic predisposition for low-IQ/crime" cannot be passed off as benign. It can & has been weaponised politically. See Philip Kitcher: https://twitter.com/EPoe187/status/1218987158586916864 …pic.twitter.com/qz9vpjB5no
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James Lingford proslijedio/la je Tweet
Gene expression levels are continuous rather than binary. To access biological phenotypes along such a continuum, we developed a method to titrate gene expression using systematically attenuated CRISPR guide RNAs. Check out our work in
@NatureBiotechhttps://twitter.com/NatureBiotech/status/1216783377539510274 …
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Predictable properties of fitness landscapes induced by adaptational tradeoffs
https://www.biorxiv.org/content/10.1101/2020.01.15.908574v1.abstract?%3Fcollection= …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
James Lingford proslijedio/la je Tweet
It's time to replace λBeta in MAGE, DIvERGE and ssDNA recombineering! By analyzing 100s of proteins, we have identified 2 that allow E.coli oligo-recombineering with up to 50% efficiency, increase multiplexability + allow MAGE in P. aeruginosa https://www.biorxiv.org/content/10.1101/2020.01.14.906594v1 …pic.twitter.com/2h1yPjQbia – mjesto: Harvard Medical School New Research Building
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Evolutionary trend toward kinetic stability in the folding trajectory of RNases H 'despite large sequence divergence, the overall folding pathway is conserved over billions of years of evolution' https://www.pnas.org/content/early/2016/10/28/1611781113 …pic.twitter.com/GuOxMDXCf2
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James Lingford proslijedio/la je Tweet
There is an article in
@WSJ today against me https://www.wsj.com/articles/cancel-culture-comes-to-science-11578867753?mod=flipboard …. My timeline is now filled with insults and questions. I will not be responding individually, hence this thread. 1/Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi
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