Jason Scapa, MD

@JScapaPathMD

Gen Surg Path Fellow . Former Pathology Chief Resident and CAP RFEC Secretary. Tweets =/= medical advice.

Vrijeme pridruživanja: rujan 2016.

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  1. 1. velj

    Alright that’s it from here in Sunny Phoenix from the Council on membership and professional development committee meetings. Have a great weekend.

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  2. 1. velj

    Prognosis depends on parasite burden, chronicity or risk of reinfection. Left untreated, schisto can cause hydronephrosis, pyleonephritis, and renal failure. Also remember the risk of progression to carcinoma, especially squamous cell.

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  3. 1. velj

    Treatment is short course of praziquantel.

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  4. 1. velj

    Differential includes encrusted cystitis or microspheres from selective internal radiation. Both of these give calcifications that mimic ova.

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  5. 1. velj

    Also mansonii and japonicum like intestinal infections.

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  6. 1. velj

    Microbio: speciation is possible on histology. The main three species are haematobium, japonicum, and mansonii. The presence and location of a spine is the distinguishing factor. Haematobium has a terminal spine, mansonii has lateral spine, and japonicum has no spine.

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  7. 1. velj

    Boards fact: Schisto is associated with keratinizing squamous metaplasia and dysplasia which can turn into primary squamous cell carcinoma of the bladder. Urothelial and adenocarcinoma can also be seen.

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  8. 1. velj

    Histology shows ova with inflammatory response composed of granulomas with acute and chronic inflammation including eosinophils. Sometimes only the calcified eggs are seen.

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  9. 1. velj

    The organism ova are deposited in veins of the muscularis propria of the bladder where to become permeable. The organisms infiltrate bladder tissue and incite a robust inflammatory reaction.

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  10. 1. velj

    CP lab tests include looking for eggs in urine or ELISA tests for Schisto antigens.

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  11. 1. velj

    Most common presentation is hematuria. The incidence is highest in patients from or visiting sub-Saharan Africa or the Mediterranean. Cystoscopy shows sandy patches of rough granular mucosa. Ulceration may be present but polyps are not common.

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  12. 1. velj

    This was a fantastic example of active schistosomiasis. 🧫Our microlab confirmed these larvae as Schistosoma haematobium.

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  13. 1. velj

    . Saturday! 📝30 YO woman returning from Zambia with hematuria. Cystoscopy shows a bladder “nodule”. 🔬Acute and chronic cystitis with abundant eosinophils. Ova and helminths are seen.

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    1. velj

    ⁩ ⁦ Council on Membership and Professional Development ⁦⁩ ⁦⁩ ⁦⁩ ⁦⁩ ⁦⁩ ⁦⁩ ⁦

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  15. 31. sij

    We have some fantastic content ideas for 2020 geared towards New in Practice Pathologists as well as highlighting the tangible and intangible benefits provides its members. Stay tuned!

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  17. 31. sij
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  18. proslijedio/la je Tweet
    30. sij

    1/ Here by popular demand “How to Publish in Academics When Publishing Isn’t Your Thing”. A on the picking & publishing low-hanging fruit in academic medicine. Further input always welcome. By no means complete. Hope it helps. Thread…

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  19. proslijedio/la je Tweet
    14. lis 2019.

    85% of patients are interested in meeting with to discuss their pathology report, according to a survey conducted at

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  20. proslijedio/la je Tweet
    28. sij

    Register now for Spring 2020 Residents Forum meeting, all residents and medical students welcome to attend! Registration is free!

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