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Prikvačeni tweet
It's out! Our new
@PNASNews paper from the NeuroSensory Biomarking Laboratory@TheNeuro_MNI@mcgillu "Reactivation of critical period plasticity in adult auditory cortex through chemogenetic silencing of PV+ [cells]" https://www.pnas.org/content/early/2019/12/10/1913227117 … Funding:@CIHR_IRSC and@theCRBLMHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
MikeCF proslijedio/la je Tweet
Types of peer review: 1) 3 anonymous scientists write secret reviews in a process that takes a few months 2) dozens of known experts write comments that anyone in the world can see hours after a paper is posted (e.g this thread
)
Explain to me again why is 1 >> 2?https://twitter.com/trvrb/status/1223666856923291648 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
MikeCF proslijedio/la je Tweet
Mi papá tiene 60 (SESENTA años) y ayer aposto con sus amigos a qué, si se rapaba, cada uno de ellos lo invitaba a cenar un día diferente. Los hombres no crecen amigos, NO CRECEN. Mi papá está MAL RAPADO y parece que lo masticó una vaca. AH PERO FELIZ CON SUS 10 CENAS GRATIS
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MikeCF proslijedio/la je Tweet
Si tan solo tuviéramos un avión...
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MikeCF proslijedio/la je Tweet
Again and again, reporters ask me: "Why all the vitriol? It's just a work of fiction." Ah, privilege. What a drug. If you didn't grow up Mexican American in a Mexican American community, you didn't spend your childhood hearing about (& experiencing) the harm done to us. 7/
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MikeCF proslijedio/la je Tweet
De esos chistes que codicias. Te odio porque te amo
@alarcondibujos.pic.twitter.com/vE4webiMHn
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Yup, language matters: "words carry our assumptions and project stigma and shame" Important to consider today on
#BellLetsTalk
#BellLetsTalkDay and going forward.https://twitter.com/choo_ek/status/1222276791806480384 …
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As time goes by, learning new things might get harder, but not impossible. Keep on learning! And stay tuned for future updates! Grateful for the support from
@CIHR_IRSC@NSERC_CRSNG@Conacyt_MX@theCRBLM@FRQ_NT who made the study possible! 10/10Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
I believe this approach can interestingly be generalized to other studies on perceptual learning (e.g. visual, tactile, etc) & be extended to other modalities (motor learning, memory...). 9/
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Our study is the first to use PET scans in rodents to demonstrate how perceptual learning changes cholinergic function in a region-specific manner. For more details and pretty figures, check out our full
#openaccess paper@FrontiersIn@FrontNeurosci https://www.frontiersin.org/articles/10.3389/fnins.2019.01438/full … 8/pic.twitter.com/sITwj2PDEH
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With this study, we have shown that:
intensive training can lead to significant learning even in the very old brain
auditory training resulted in increased cholinergic function specifically in the brain area that processes sounds
7/pic.twitter.com/b3zEwBhEUkPrikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
After training, we found an increase in cholinergic activity specifically in the part of the brain that deals with hearing
but not in other brain areas.
We concluded that yes, the cholinergic system itself changed with training.
6/pic.twitter.com/KCDyccbEsw
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We also scanned their
before/after training to map changes in their cholinergic system.
We used an imaging test called PET scan. On these scans, the brain areas with greater cholinergic activity showed up as bright spots.
What did we find, you ask?
6/pic.twitter.com/ltEYoPMcgD
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We trained old rats
to identify different sounds
Each time they identified the 'target sound' they got a chocolate pellet
. If they got it wrong, they just had to wait for a few seconds for their next chance.
Attention?
Motivation?
#TheyLearned#ChocolateFTW 5/pic.twitter.com/R7I8Mh9owl
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Also, there was another question that kept bugging us: Tons of
#neuroscience studies have shown that activation of the cholinergic system remodels the brain, but does the cholinergic system 𝑖𝑡𝑠𝑒𝑙𝑓 change with learning? Here's what we did to address these questions... 4/pic.twitter.com/mEfEgKiSqk
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Perceptual learning is facilitated by the 𝐜𝐡𝐨𝐥𝐢𝐧𝐞𝐫𝐠𝐢𝐜 𝐬𝐲𝐬𝐭𝐞𝐦, an ensemble of brain cells that enhance attention & motivation. But the cholinergic system degenerates w/ age, making learning
harder as we grow older
Can we help older brains learn better?
3/Prikaži ovu nitHvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
W/ practice, we can become better at distinguishing between diffrent sounds
, images
...
This process, called 𝐩𝐞𝐫𝐜𝐞𝐩𝐭𝐮𝐚𝐥 𝐥𝐞𝐚𝐫𝐧𝐢𝐧𝐠
, supports language acquisition, musical expertise, and even professional judgments, such as the interpretation of X-rays
2/pic.twitter.com/WaVtD8n3oo
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They say u can’t teach old
new tricks but our research shows u can teach old
new sounds!
A thread on our new paper @FrontNeurosci, an effort by 10 scientists, 4 labs@mcgillu@UMontreal@TheNeuro_MNI@DouglasResearch https://www.frontiersin.org/articles/10.3389/fnins.2019.01438/full …#ScienceTwitter#SciCommDay 1/pic.twitter.com/T41CPqxar4
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MikeCF proslijedio/la je Tweet
Study published by
@JMCisFran@KangMSPeter@maryseethomas@cotejonathan@pedrorosaneto et al. shows that#perceptual#learning is linked to region-specific changes in#cholinergic#neurotransmission. Read more here: http://fro.ntiers.in/wxQQ@mcgillu@TheNeuro_MNI@DouglasResearchpic.twitter.com/gjIIKJbdHv
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A great tool to improve accessibility: "Color Universal Design (CUD) - How to make figures and presentations that are friendly to Colorblind people -"
@HBHLMcGill#ScicommDay@SciCommArt@HBHL_Trainees https://jfly.uni-koeln.de/color/#redundant2 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi -
MikeCF proslijedio/la je Tweet
Nice to see a new preprint from
@ChiaraFabbri12 and colleagues re#pharmacogenomics for#antidepressant response
.
Polygenic risk scores do not predict antidepressant response #yet. However patients with high genetic risk for schizophrenia more likely to be non-respondentshttps://twitter.com/medrxivpreprint/status/1218490081876566019 …Hvala. Twitter će to iskoristiti za poboljšanje vaše vremenske crte. PoništiPoništi
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