Ian Setliff

@IanSetliff

Antibodies & computational immunology. and alum. Computational Immunology & Genomic Data Science at Regeneron. Views mine.

New York, NY
Vrijeme pridruživanja: srpanj 2015.

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  1. proslijedio/la je Tweet

    virus vaccination elicits Zika and virus cross-neutralizing in -exposed individuals, potentially enhancing the protective efficacy of the vaccine in flavivirus-endemic regions

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  2. proslijedio/la je Tweet
    3. velj

    Study led by WRAIR’s Emerging Infectious Diseases Branch finds Army-developed Zika vaccine induces potent Zika and dengue cross-neutralizing antibodies.

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    3. velj

    ”A large leap forward can be made if the immunotherapy target cells and pathways are characterized at high resolution before and after treatment, in clinical cohorts and model systems” Single-cell biology is about to eat drug development too!

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  4. proslijedio/la je Tweet
    29. sij

    Our exciting new collaboration with and our partners at USAMRIID. Examining the structure and role in pathogenesis of CCHFV GP38

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    Memory B Cell Activation, Broad Anti-influenza Antibodies, and Bystander Activation Revealed by Single-Cell Transcriptomics - ScienceDirect

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  6. 19. sij
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  7. 12. sij

    I couldn't have had a better time during my PhD thanks to the incredible mentorship of , my awesome labmates, our many great collaborators near and far, and the friends I made along the way. Thanks to all who made science so fun the last few years!

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    6. sij

    Happy New Year! We are excited to share two upcoming dissertation defenses from Marion Sauer, from and labs, and , from ! Make sure to check out the amazing discoveries they made.

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    3. sij

    An amazing story. If you take BCG, a 100 year old vaccine given intradermally with limited success, and give it intravenously, it induces robust T cell and antibody immunity that is highly protective (9/10 protected) against tuberculosis!

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    20. pro 2019.

    The discovery & development research fields may be on the verge of rapidly expanding with data that previously took decades, thanks to LIBRA-seq, a new tool developed by researchers & their colleagues. Learn more:

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    17. pro 2019.

    A new tool, LIBRA-seq, may upend discovery and development by simultaneously mapping antibody sequences and antigen specificities in a high throughput way. explains the technology in .

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    13. pro 2019.

    A good example of why pursuing innovative, yet high-risk, should not only be encouraged and supported, but consistently prioritized, at all levels (PIs, institutions, funding agencies). Grateful for the amazing team in this study, led by and .

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    13. pro 2019.

    has developed a new resource called LIBRA-seq, “Linking B-cell Receptor to Antigen Specificity through sequencing,” and has leveraged the technology to identify a previously unknown broadly neutralizing HIV antibody.

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  14. proslijedio/la je Tweet

    : paper in is making a splash! "High-Throughput Mapping of B Cell Receptor Sequences to Antigen Specificity" -

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  15. proslijedio/la je Tweet
    9. pro 2019.

    Researchers from have developed LIBRA-seq, a method that leverages single cell immune sequencing to rapidly link B-cell receptors with their corresponding antigens. Hear from the lead author in a recent webinar & explore the paper on our blog.

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  16. 9. pro 2019.
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    A breakthrough in developing an effective HIV vaccine by researchers at & , whose study show that antibodies can be coaxed into multiplying as protective force against the virus. Congrats to all involved in this exciting discovery!

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    7. pro 2019.
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  19. proslijedio/la je Tweet
    28. stu 2019.

    Not sure what to do after that big Thanksgiving day meal? Read our fun new paper in : High-Throughput Mapping of B Cell Receptor Sequences to Antigen Specificity

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    A Randomized, Controlled Trial of Virus Disease Therapeutics | NEJM

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