The ICROvjeren akaunt

@ICR_London

The Institute of Cancer Research is making the discoveries that defeat cancer. We're the UK's top academic research centre, a postgrad college, and a charity.

London, UK
Vrijeme pridruživanja: prosinac 2011.

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  1. Prikvačeni tweet

    Today we launch our annual ! 🔬📸🦠 In this thread, we'll showcase 8 images, which tell vivid stories about our science, and depict the use of a range of scientific techniques. The images were taken by researchers at the ICR & . 1/11

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  2. It's 🌍🔬🙌 The ICR has been driving scientific discoveries on cancer and its treatment for more than 100 years. Find out more about all the ways we're working to defeat cancer:

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  3. Projects such as our are made possible by an extraordinary community of generous donors, which includes individuals, trusts and foundations and charity partners. Find out more about philanthropy at the ICR:

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  4. To wrap up the thread, once again please like ❤️ your favourite image before the deadline of 9am on 14 February. Once you've voted, why not take a look at our magnificent entries from our previous two years at 11/11

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  5. Image 8 of 8: Forward and reverse translation Tumour organoids are mini replicas of a patient’s tumours, and could be used to rapidly test a patient’s cancer against a range of cancer drugs to see which ones may be most effective. 10/11

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  6. Image 7 of 8: ‘The Art of Deception’. These aggressive cells look like structures normally seen in healthy breast tissue. Cancer uses deception to hide from the immune system and avoid treatment. 9/11

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  7. Image 6 of 8: Super-resolution microscopy image of cell focal adhesions The first ever super-resolution microscopy image taken of focal adhesions – molecules inside cellular structures which help cancer cells move and spread around the body. 8/11

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  8. Image 5 of 8: Invading melanoma cell in 3D. A cell from aggressive is growing into and around fibres of collagen, mimicking how cancer invades tissue. Cancer remodels its environment to spread around the body. 7/11

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  9. Image 4 of 8: Differentiating brain cancer cells Cells from aggressive have been treated with compounds to change how they develop, which could help to make the disease easier to treat. 6/11

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  10. Image 3 of 8: Dimpled ‘golf ball-like’ microparticles could help prevent cancer spread. These microscopic gold-plated particles are dimpled like golf-balls, and the texture of their surface could control how cells grow and divide, and potentially help treat cancer. 5/11

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  11. Image 2 of 8: Melanoma on a chip. Part of a melanoma cell has been blasted away using a technique called ion beam milling. This process helps researchers look inside cells in unprecedented detail, to help them understand the processes happening inside. 4/11

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  12. Image 1 of 8: The eye of the storm: the tumultuous, dramatic nature of cancer tumours. Lab grown mini-tumours are better at capturing the unique characteristics of tumours in patients, and can be used to understand how they might respond to cancer drugs. 3/11

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  13. The image with the most likes (combined across our social media channels) will win the public vote. Check out the 8 incredible images in our thread, and like ❤️ your favourite. The deadline is 14 February at 9am. 2/11

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  14. You can find out more about we use chemical probes at the ICR by reading this Science Talk blog post by from last November:

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  15. Also included in the list of resources is Probe Miner, a resource developed by the ICR:

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  16. The webinar highlights several useful chemical probes resources. This includes the Chemical Probes Portal (co-founded by the ICR):

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  17. Blagg and Workman's work is referenced again in this slide on the 'Dos and Dont's of chemical probes':

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  18. The webinar also references work by ICR Professors Paul Workman and Ian Collins:

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  19. Slide 6 in this webinar references the published work of the ICR's Professor Paul Workman and (former ICR Team Leader), Professor Julian Blagg:

    Slide from presentation by @EuroMedChem
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  20. Chemical probes can be used to test the role of a particular protein in diseases such as cancer, and to help validate that protein as a target for future drugs.

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