The Hodges Lab

@Hodges_Lab

Research group in Biochemistry and Human Genetics at - Our research strives to understand how epigenetic features shape human genomes 🧬🧫🔬

Nashville, TN
Vrijeme pridruživanja: kolovoz 2019.

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  1. Prikvačeni tweet
    29. sij

    Very excited to present our findings and ATAC-Me method published today in Molecular Cell! Huge congrats to first-author Kelly Barnett, who developed the ATAC-Me technique. ATAC-Me measures DNA methylation across the dynamic chromatin accessible genome.

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  2. proslijedio/la je Tweet
    30. sij

    Emily Hodges has been doing great work on DNA methylation since her days at . I always liked this 2011 work on the expansion and contraction of hypomethylated regions during haematopoietic differentiation:

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  3. proslijedio/la je Tweet
    30. sij

    First the chromatin opens, then the DNA methylation is lost. The chromatin opens because transcription factors (TFs) target those loci. TFs tell DNA methylation and nucleosomes what to do at cis-regulatory loci. Not the other way around. Your textbook needs a rewrite.

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  4. proslijedio/la je Tweet
    30. sij

    Introducing ATAC-Me, "which probes accessibility and methylation from single DNA library preparations." Congrats !

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  5. proslijedio/la je Tweet
    29. sij
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  6. 16. pro 2019.

    Jolly times with a great group of scientists. Happy Holidays everyone! 🎄🍻🧬

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  7. proslijedio/la je Tweet

    Starting soon, so run along, run along!! PI Emily Hodges will present the next PDB Journal Club. She has selected a paper from focused on heterogeneity in old fibroblasts and its relation to reprogramming and wound healing. 4pm in 3131 MRBIII.

    Flyer for the Program in Developmental Biology journal club. Emily Hodges will present a paper titled, "Heterogeneity in old fibroblasts is linked to variability in reprogramming and wound healing," by Mahmoudi et al. Full citation: "Nature. October 2019, 574, pg 553-558 10.1038/s41586-019-1658-5." An abstract and the paper's Figure 1 are included below the title.
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  8. 19. stu 2019.
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  9. 15. stu 2019.
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  10. proslijedio/la je Tweet
    11. stu 2019.

    Hey Vandy peeps! Biochem's GSA is sponsoring this week's tailgate on Saturday Nov. 16 at 11AM! Come hang out and get some food before heading to the game. Location: last two tents of Vandyville on Dudley Ave -BSA Social Committee , Ivette Perez, ,

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  11. proslijedio/la je Tweet

    Thanks to Tim Scott of the for his Genetics Interest Group Presentation, "Modular architecture of DNA hypomethylation at putative lymphocytic super enhancers reflects cell type-specific gene regulation"

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  12. 7. stu 2019.
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  13. proslijedio/la je Tweet
    8. lis 2019.

    Check out our latest work in . Kristy Stengel utilized mouse models and selective inhibitors in DLBCL cell lines to define the role of HDAC3 in germinal centers and B-cell maturation.

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  14. proslijedio/la je Tweet
    8. lis 2019.

    Fresh paper out of Tony Capra's lab: "Inferred divergent gene regulation in archaic hominins reveals potential phenotypic differences" in ! His lab uses a new computational method to ID gene regulatory differences between archaic hominins & modern humans

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  15. proslijedio/la je Tweet
    7. lis 2019.

    Our seminar speaker this Wednesday is Tony Capra! Join us at 4:10pm on Oct. 9 to hear his talk and learn the answer to a puzzling question: "My Ancestor Was a Neanderthal. Should I See a Doctor?" Hope to see you there!

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  16. proslijedio/la je Tweet

    Did you know that Lau () was planning on being a after college? Even though he's become a prolific scientist, his current work still reminds him of his old passions. Listen to him explain some of the similarities. 🎮🧫🔬

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  17. 7. ruj 2019.
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  18. proslijedio/la je Tweet
    5. ruj 2019.

    Excited for the PDB retreat today!

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  19. 29. kol 2019.
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  20. proslijedio/la je Tweet
    26. kol 2019.

    Join us on Thursday, September 12 at 4 pm in 208 Light Hall for a Flexner Discovery Lecture by the 2019 Vanderbilt Prize Winner, Dr. Christine Seidman!

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