cousin marriage to show up higher on this graph even in populations with greater genetic diversity present in the population as a whole?
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Replying to @HbdNrx @JayMan471
it's tricky, 'cause other things can also make pops more homogeneous or not (in their dna) like bottlenecks. so pops in americas very...
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...similar genetically speaking, 'cause they went thru huge bottleneck of migrating to the new world.
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the different processes (say bottlenecks vs. cousin marriage) do leave different signatures in pop genomes, tho, in varying lengths in...
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...runs of homozygosity (roh). here you can see that new world pops share a lot of short roh (bottleneck) while middle easterners...pic.twitter.com/u39XDALglj
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...share a lot of medium length roh thanks to inbreeding. so, there's diff sorts of varation in homizygosity for diff reasons.
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Replying to @hbdchick @JayMan471
So, in this data overall it looks like the effects of human migration out of Africa are dominating any recent cousin marriage practices, but perhaps if we compare the 1-2Mb range to the 4-8Mb range there we can see how more recent practices are reducing the Euro and East Asian
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bars. That is, the Euro and East Asian bars drop much more than some other groups as we move up from the 1-2Mb range. We would expect the ratio of short to long ROH to decline with more recent inbreeding.
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You're thinking about two different things. IBD vs ROH.
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IBD = inbreeding? Inbreeding should lead to longer runs of homozygosity, the most recent the longer.
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Identity by descent. It's a way of assessing overall genetic variation in a population. Inbreeding doesn't affect it much.
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