Haematologica

@Haematologica

Haematologica: the journal of the Ferrata Storti Foundation

Pavia, Italy
Vrijeme pridruživanja: svibanj 2012.

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  1. 4. velj

    Fibrinogen and fibrin are implicated in different disorders. Which are the mechanisms that may contribute to disease?

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  2. 1. velj

    February issue is available online. See and download for free the Haematologica Digital Edition!

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  3. 31. sij

    The demographic and clinical characteristics of extramedullary disease (extramedullary plasmacytoma or paraosseous involvement) among 226 myeloma patients at initial diagnosis or relapse and its impact on treatment outcomes.

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  4. 28. sij

    In order to clarify the role of new drugs in MM with extra-medullary disease, Montefusco et al. conducted the largest meta-analysis so far reported, based on eight prospective trials by the same sponsors.

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  5. 25. sij

    The strong and selective anti-leukemia activity of APR-246 in TP53-mutated ALL provides the basis to develop personalized therapy regimens for this high-risk subgroup of ALL.

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  6. 21. sij

    Smog e Malattie cardiovascolari Il particolato, in particolare quello più fine, causa tumori, patologie respiratorie e soprattutto cardiovascolari. E i limiti Ue sono ancora troppo elevati. L'allarme dei ricercatori italiani: più infarti e ictus

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  7. 19. sij

    These data expand our understanding of the potential mechanisms initiating enhanced IL-6 production in mastocytosis and emphasize targets for therapeutic intervention in cases of high IL-6 profiles and suspected disease progression.

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  8. 16. sij

    Homoharringtonine (HHT) - a cytotoxic alkaloid approved by the US FDA for treatment of CML – for the treatment of AML carrying FLT3 mutations and/or with overexpression of endogenous TET1/FLT3/HOXA9/MEIS1.

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  9. 13. sij

    These data demonstrate the BCR-ABL1-specific, cell-intrinsic pathways leading to altered interactions with the vascular niche via the modulation of adhesion molecules – which could be exploited therapeutically in the future.

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  10. 10. sij

    Available evidence on the use of donor lymphocyte infusion from haploidentical donor, and recommendations on its therapeutic, pre-emptive and prophylactic use in clinical practice.

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  11. 7. sij

    Research on intrinsic mechanisms responsible for HSC aging is providing, and will continue to provide, new potential molecular targets to possibly ameliorate or delay aging of the hematopoietic system.

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  12. 4. sij

    The crosstalk between hematopoietic stem cells and the microenvironment is indispensable for the aging of the hematopoietic system and might represent a therapeutic target in age-related pathological disorders.

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  13. 1. sij

    January issue is available online. See and download for free the Haematologica Digital Edition!

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  14. 28. pro 2019.

    Preferential pro-apoptotic responses of CLL cells to a second-generation and clinically relevant MDM2 inhibitor (RG7388) exposure, compared with those of normal hematopoietic cells.

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  15. 23. pro 2019.

    Perturbations in DNA damage response pathways in FLT3-ITD AML could be harnessed to provide novel strategies for the treatment of this aggressive neoplasm.

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  16. 21. pro 2019.

    Potentially pathogenic somatic variants of epigenetic modifiers are common in CML-CP at diagnosis, and when combined with other risk factors may be promising predictive biomarkers determining which is the best TKI for each individual.

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  17. 17. pro 2019.

    An Atlas of Hematology celebrates the Centenary of the free scientific journal, Haematologica. It had 9 million visitors to its website just in 2018. Haematologica is an Open Access journal that aims to promote research into blood diseases and treatments.

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  18. 17. pro 2019.

    The results of this study establish the MBD2 Nucleosome Remodeling and Deacetylase complex as a major silencer of fetal hemoglobin in human erythroid cells

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  19. 13. pro 2019.

    This manuscript proposes practical considerations for the use of CAR-T cell therapy in Multiple Myeloma, and discusses several important issues for its future development.

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  20. 9. pro 2019.

    The global mortality and morbidity burden of cardiovascular disease associated with air pollution, particularly for the PM2.5 size fraction, is dramatically greater than what has been thought up to now.

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