And people make them. We just can't enforce them on everyone or agree on them and so the meaning generally remains a vague & fluffy "characteristics, identities & behaviours which are associated with sex but are not biological organs."
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https://link.springer.com/article/10.1007/s10508-016-0768-5 … Granted there is only one study on non-homosexual MtFs, but it did show them to have regular male brains in regions where male and female brains differ. They did have some brain difference from other people, but not in regions where M and F brains differ.
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