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HCCvPDAC's profile
Howard Crawford
Howard Crawford
Howard Crawford
@HCCvPDAC

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Howard Crawford

@HCCvPDAC

I research and I know things. Pancreatic cancer can get bent! Views expressed not attributable to my employer (except the one about trying to eradicate PDAC)

Ann Arbor, MI
Joined November 2017

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    1. Howard Crawford‏ @HCCvPDAC Aug 15

      One reviewer clearly doesn’t believe in cellular plasticity so trashes one of the aims, calling it “farfetched”. (Oooh, but of course in the past couple of months we’ve finished that aim and it’s even cooler than we could have hoped. BTW, where did *that* money come from?). /26

      2 replies 0 retweets 38 likes
      Show this thread
    2. Howard Crawford‏ @HCCvPDAC Aug 15

      Oh, yes… and the proposal is not translational enough. /27

      1 reply 0 retweets 17 likes
      Show this thread
    3. Howard Crawford‏ @HCCvPDAC Aug 15

      Another reviewer clearly thought that reviewer was insane and had nothing but nice things to say. These reviewers ARE out there, people! Marry them if you have to. No wait, then they’d be COI. Don’t marry them./28

      2 replies 3 retweets 102 likes
      Show this thread
    4. Howard Crawford‏ @HCCvPDAC Aug 15

      The last reviewer was nice, if a little wishy washy. They criticized 1 aim pretty harshly because I didn’t have the 6 allele mouse I needed in hand. NOT that the alleles haven’t been *created* yet. Just that they have not been BRED together yet. If only @DrBenNeel were there!/29

      2 replies 0 retweets 20 likes
      Show this thread
    5. Howard Crawford‏ @HCCvPDAC Aug 15

      Oh and show data from those mice. In other words, “finish the aim, then we’ll talk.”/30

      1 reply 0 retweets 37 likes
      Show this thread
    6. Howard Crawford‏ @HCCvPDAC Aug 15

      BTW, this was the reviewer that said I didn’t address sex as a biological variable when there was an entire paragraph about it. FYI, I underlined that paragraph without explanation in the resubmission because... I’m the devil./31

      3 replies 1 retweet 52 likes
      Show this thread
    7. Howard Crawford‏ @HCCvPDAC Aug 15

      Cool new data added. Even preliminary data for “where’s your 6 allele mouse model” reviewer. I should be confident, right? So why not? Because there’s only a negligible chance the A1 will see any of the same reviewers. /32

      1 reply 0 retweets 17 likes
      Show this thread
    8. Howard Crawford‏ @HCCvPDAC Aug 15

      Mo reviewers, mo problems. I know. I’ve been there. As a reviewer, I sweat bullets when I read the Intro and see they’ve been very responsive, but the advice was… just bad./33

      1 reply 1 retweet 26 likes
      Show this thread
    9. Howard Crawford‏ @HCCvPDAC Aug 15

      Then I read the grant and see fundamental mistakes that I can’t ignore. I totally forgive cases where I simply have a different opinion. If you’re responsive and there’s not fatal flaw, you’re golden with me. /34

      1 reply 2 retweets 28 likes
      Show this thread
    10. Howard Crawford‏ @HCCvPDAC Aug 15

      I hate to tell you this young ‘uns, but that’s really not the norm. And all it takes is one reviewer./35

      2 replies 1 retweet 32 likes
      Show this thread
      Howard Crawford‏ @HCCvPDAC Aug 15

      And therein lies the problem. With an 8% pay line, all it takes is one reviewer. One reviewer who doesn’t have the right knowledge base. One reviewer who simply isn’t excited about your proposal. One reviewer who says “it’s not translational enough”. /36

      12:07 PM - 15 Aug 2019
      • 23 Retweets
      • 143 Likes
      • Rejji Kuruvilla Vinee Purohit Leigh Knodler Ashi_W Stephen Floor Daniel Moore Samarth Hegde Henning Willers, MD John Charpentier
      5 replies 23 retweets 143 likes
        1. New conversation
        2. Howard Crawford‏ @HCCvPDAC Aug 15

          One reviewer who had to comment on 10 other grants. One reviewer who was taking care of a sick kid and missed some major points./37

          2 replies 0 retweets 37 likes
          Show this thread
        3. Howard Crawford‏ @HCCvPDAC Aug 15

          A stressed reviewer in a room full of stressed reviewers. Panel members who feel like they don’t have the expertise to make an informed decision, so they vote down the middle, with boundaries set in part by that one reviewer. That’s all it takes./38

          1 reply 4 retweets 55 likes
          Show this thread
        4. Howard Crawford‏ @HCCvPDAC Aug 15

          By the time you’ve got your reviews, it will likely be the better part of a year before you can resubmit. And wait. And hope you won the reviewer lottery. At least this time. Did I say "lottery"?/39

          1 reply 0 retweets 32 likes
          Show this thread
        5. Howard Crawford‏ @HCCvPDAC Aug 15

          Is the system broken? You know the answer to that./40

          1 reply 1 retweet 27 likes
          Show this thread
        6. Howard Crawford‏ @HCCvPDAC Aug 15

          End rant. I'd say "Thanks for coming to my Ted Talk" but I'm pretty sure Ted Talks are shorter./end

          8 replies 0 retweets 45 likes
          Show this thread
        7. Howard Crawford‏ @HCCvPDAC Aug 15

          I failed to mention that I didn’t bother to resubmit. Waste of time. Went to a new A0, which got the 12%

          2 replies 0 retweets 25 likes
          Show this thread
        8. Howard Crawford‏ @HCCvPDAC Aug 15

          Ack, I didn’t resubmit the *ND*! All others are worth resubmitting

          4 replies 0 retweets 24 likes
          Show this thread
        9. End of conversation
        1. New conversation
        2. Kevin Wright‏ @kevinmawright Aug 15
          Replying to @HCCvPDAC

          At 8% it’s even worse... all the reviewers could like it, but just not “love” it as much as even 1 other grant in their pile. Totally unsustainable.

          1 reply 0 retweets 5 likes
        3. Howard Crawford‏ @HCCvPDAC Aug 17
          Replying to @kevinmawright

          Yup. The enthusiasm gap. Nothing you can fix or address. Just send it to another study section as is and hope for 7 or 11.

          0 replies 0 retweets 0 likes
        4. End of conversation
        1. New conversation
        2. Brooke Jennings‏ @Brooksie1Jenn Aug 17
          Replying to @HCCvPDAC

          Or they blatantly ignore the PDAC data as in my case. Pretended it didn’t exist 😥. We just have so much activity across the board. I guess they weren’t happy with that and didn’t want to ask questions. So, yeh. I hate grant writing. Big waste of my time.

          1 reply 0 retweets 1 like
        3. Howard Crawford‏ @HCCvPDAC Aug 17
          Replying to @Brooksie1Jenn

          Sorry to hear that. But I’m still a believer in grant *writing*, just not the process that follows.

          1 reply 0 retweets 1 like
        4. Brooke Jennings‏ @Brooksie1Jenn Aug 17
          Replying to @HCCvPDAC

          I understand. I’ll just never be able to wrap my arms around the blatant bias and gate-keeping agenda.

          0 replies 0 retweets 0 likes
        5. End of conversation
        1. Louise Giam‏ @LouiseGiam Aug 16
          Replying to @HCCvPDAC

          OMG this is why the next generation is concerned about doing science

          0 replies 0 retweets 2 likes
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        1. New conversation
        2. Paneez Khoury MD‏ @KhouryMD Aug 17
          Replying to @HCCvPDAC

          @threadreaderapp unroll this craziness please

          2 replies 0 retweets 0 likes
        3. Thread Reader App‏ @threadreaderapp Aug 17
          Replying to @KhouryMD

          Hello, the unroll you asked for: Thread by @HCCvPDAC: "Is the NIH grant system broken? Shockingly, I have thoughts. Thoughts from both sides of the process, grantee and review […]" https://threadreaderapp.com/thread/1162076390226681856.html … Share this if you think it's interesting. 🤖

          0 replies 0 retweets 1 like
        4. End of conversation

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