How to be wrong, in 8 words It wasn't a cause, it was a plausible mechanism And you forgot to add "IN MICE" to the end of the sentencepic.twitter.com/wP7FY6v7Df
Epidemiologist. Writer (Guardian, Observer etc). "Well known research trouble-maker". PhDing at @UoW Host of @senscipod Email gidmk.healthnerd@gmail.com he/him
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How to be wrong, in 8 words It wasn't a cause, it was a plausible mechanism And you forgot to add "IN MICE" to the end of the sentencepic.twitter.com/wP7FY6v7Df
Here's the study. Researchers found that pregnant women with PCOS had a higher level of a hormone. They then gave this hormone to mice, and saw changes similar to PCOS in the children of these micepic.twitter.com/0myiPb7wO9
They then tested a treatment on these mice, and found that they could reverse the issues caused by this hormonepic.twitter.com/nNdm1TXpGu
Does this mean that this is "The Cause" of PCOS? Obviously not. We don't know yet if this mouse model transfers to humans
The treatment, especially, is at its very formative stages, and is likely only useful for a small subset of women with PCOS
So we still don't know if a) this is the cause of all PCOS, or just one mechanism by which PCOS can occur or b) if this mechanism transfers from the rodent to the human model, or if it works differently in people
We also don't know if the treatment they've identified has any utility in humans at all - it's still very early days
Link to the study here: https://www.nature.com/articles/s41591-018-0035-5.epdf …
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