Not at all. I'm just pointing out that the many grams of orally-ingested aluminium is circulating in your blood well before it is excreted. How is the phagocytosis of aluminium circulating in your blood before elimination via the kidneys different to that of intramuscular Al?
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Replying to @GidMK @Rebekah60291919
Right of the bat, only 0.1%-0.78 % orally ingested aluminum passes through the small intestine into systemic circulation. So for 8.64 mg orally ingested over 9 months, (using 0.78 %) only 67.3 ug enters circulation and 8.57 mg goes into feces. Agree?
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The gut generally is an effective barrier to aluminum salt uptake.
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Replying to @rightwingblack2 @Rebekah60291919
Oddly enough, several studies postulate a much higher aluminium intake orally than you've suggested, more in line with 0.7mg/day or 125mg/6 months, of which 0.78% would of course be ~1mg https://www.tandfonline.com/doi/abs/10.1080/02652039509374286 …
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Anyway, let's put that aside for the moment because you were super keen to tell me how phagocytes transfer intramuscular aluminium to the brain. Sounds super cool!
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Replying to @GidMK @Rebekah60291919
Al Adj is phagocytized. T helper 1 (THP-1) cells that phagocytize AlOOH have low mortality. Monocytes recruited to tissues (brain, etc) releasing attracting signal CCL2. Many viruses induce CCL2. https://www.nature.com/articles/srep31578 … https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-015-0388-2 … http://journals.sagepub.com/doi/pdf/10.1177/0961203311429557 …pic.twitter.com/4YzexyjBlT
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Replying to @rightwingblack2 @Rebekah60291919
Ah yes, those definitive studies on aluminium injected into rabbit muscle tissue in vitro. What definitive proof!
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Replying to @GidMK @Rebekah60291919
Flarend proved in vivo (rabbits) translocation into the brain apparently without acceleration due to viral infection.
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Replying to @rightwingblack2 @Rebekah60291919
Proved is the wrong word, obviously. Demonstrated in a single tiny rabbit study is perhaps more appropriate. The other studies appear to be in rodent muscle
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Replying to @GidMK @Rebekah60291919
Ok...Demonstrated. More scientific work is needed. I presented a mechanism for al adj transport into the brain in large amt. relative to amount injected. Many viruses settle in the brain, induce CCL2 attracting monocytes with Al Adj. Autistic symptoms <<nuero hypoperfusion.pic.twitter.com/IO7UaADUrt
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A proposed mechanism is, essentially, one man's pointless theory Got any evidence that this actually happens?
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Replying to @GidMK @Rebekah60291919
I'm sure experiments have been conducted with results not reported/released. Inject animal (A) with al adj in muscle, X days before/after spray Herpes virus in A's nose. Record IgM, animals behavior, etc. Sacrifice A. Measure Al in brain. Control As gets Al adj injection only.
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