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GidMK's profile
Health Nerd
Health Nerd
Health Nerd
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@GidMK

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Health NerdVerified account

@GidMK

Epidemiologist. Writer (Guardian, Observer etc). "Well known research trouble-maker". PhDing at @UoW Host of @senscipod Email gidmk.healthnerd@gmail.com he/him

Sydney, New South Wales
theguardian.com/profile/gideon…
Joined November 2015

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    1. Health Nerd‏Verified account @GidMK 3 Apr 2018

      So, had a quick fun look at the California coffee/cancer claim and it's even sillier than you might imagine Follow this thread if you want to laugh at numbers

      18 replies 187 retweets 314 likes
      Show this thread
      Health Nerd‏Verified account @GidMK 3 Apr 2018

      The idea is that acrylamide in coffee might be giving people cancer, because there are a number of studies where researchers gave rodents acrylamide and this caused cancer

      5:21 PM - 3 Apr 2018
      • 1 Retweet
      • 16 Likes
      • cigarbabe Tamra 🇧🇷Guilherme Carregosa da Costa🙂 Chyna Benzine DampfFreiheit 🇩🇪💨💨💨 The Mathy Actress Dave Kiser Rumbutt@Fire V??? 何処かの馬の骨
      1 reply 1 retweet 16 likes
        1. New conversation
        2. Health Nerd‏Verified account @GidMK 3 Apr 2018

          For example https://www.sciencedirect.com/science/article/pii/0165111088900152 …pic.twitter.com/O6eu2AEW7z

          1 reply 0 retweets 9 likes
          Show this thread
        3. Health Nerd‏Verified account @GidMK 3 Apr 2018

          BUT this is contradicted by epidemiological evidence which has not found a consistent link between acrylamide cancer https://www.sciencedirect.com/science/article/pii/S0308814614002210 …pic.twitter.com/XWHC0irlSB

          1 reply 1 retweet 14 likes
          Show this thread
        4. Health Nerd‏Verified account @GidMK 3 Apr 2018

          Thus the IARC classification of 2A, meaning it's likely that acrylamide causes cancer but we aren't sure if it does yet Which might be because of the dose

          1 reply 0 retweets 16 likes
          Show this thread
        5. Health Nerd‏Verified account @GidMK 3 Apr 2018

          You see, the rats in the original studies that I linked above were getting quite a lot of acrylamide

          1 reply 0 retweets 14 likes
          Show this thread
        6. Health Nerd‏Verified account @GidMK 3 Apr 2018

          The lowest amounts where cancer was detected are about 1 mg/kg. Extrapolating to the average(ish) 75kg adult human, that's 75mg

          1 reply 0 retweets 10 likes
          Show this thread
        7. Health Nerd‏Verified account @GidMK 3 Apr 2018

          How much acrylamide is in your coffee? The CDC has some figures from the early noughties that put it at ~300ppb (parts per BILLION)pic.twitter.com/hJFJYN25L1

          1 reply 2 retweets 21 likes
          Show this thread
        8. Health Nerd‏Verified account @GidMK 3 Apr 2018

          That means that every gram of dry coffee beans has ~roughly~ 0.0000003 grams of acrylamide in it

          2 replies 2 retweets 21 likes
          Show this thread
        9. Health Nerd‏Verified account @GidMK 3 Apr 2018

          Now, brewed coffee probably has even less. But let's take that 0.0000003 grams as the figure that you'd find per milliliter of coffee

          2 replies 0 retweets 17 likes
          Show this thread
        10. Health Nerd‏Verified account @GidMK 3 Apr 2018

          Health Nerd Retweeted Health Nerd

          Let's do the maths on this 75mg figurehttps://twitter.com/GidMK/status/981328016176328704 …

          Health Nerd added,

          Health NerdVerified account @GidMK
          The lowest amounts where cancer was detected are about 1 mg/kg. Extrapolating to the average(ish) 75kg adult human, that's 75mg
          Show this thread
          1 reply 0 retweets 14 likes
          Show this thread
        11. Health Nerd‏Verified account @GidMK 3 Apr 2018

          The 0.0000003 grams figure converts to 0.0003 milligrams 75/0.0003 = 250,000 That means that using this estimate, you'd have to drink 250,000ml of coffee to get 75mg of acrylamide

          3 replies 1 retweet 23 likes
          Show this thread
        12. Health Nerd‏Verified account @GidMK 3 Apr 2018

          250,000ml is 250 LITERS of coffee For reference, that's about 500 cups That is A LOT OF COFFEE

          6 replies 6 retweets 43 likes
          Show this thread
        13. Health Nerd‏Verified account @GidMK 3 Apr 2018

          Health Nerd Retweeted Health Nerd

          I haven't even gotten to the best part yet: THIS IS A DAILY DOSEhttps://twitter.com/GidMK/status/981328016176328704 …

          Health Nerd added,

          Health NerdVerified account @GidMK
          The lowest amounts where cancer was detected are about 1 mg/kg. Extrapolating to the average(ish) 75kg adult human, that's 75mg
          Show this thread
          2 replies 3 retweets 47 likes
          Show this thread
        14. Health Nerd‏Verified account @GidMK 3 Apr 2018

          To get the amount of acrylamide FROM COFFEE that this court suggested is possibly a problem, you'd have to drink 500 cups a day I would humbly suggest that this is probably impossible

          9 replies 27 retweets 87 likes
          Show this thread
        15. Health Nerd‏Verified account @GidMK 3 Apr 2018

          P.S. here's the source for those CDC figures. The important note is that it depends on which coffee brand you pick, but since I used one of the highest readings it doesn't make much difference anywayhttps://www.fda.gov/Food/FoodborneIllnessContaminants/ChemicalContaminants/ucm053549.htm …

          1 reply 0 retweets 21 likes
          Show this thread
        16. Health Nerd‏Verified account @GidMK 3 Apr 2018

          P.P.S. the other important thing to remember is that acrylamide is found in most cooked starchy foods so you could potentially get dangerous amounts if you eat a lot of burned things but the claims from California are specifically about coffee not all food

          1 reply 1 retweet 33 likes
          Show this thread
        17. Health Nerd‏Verified account @GidMK 3 Apr 2018

          P.P.P.S forgot to mention that coffee contains caffeine, which in doses of as little as 50 cups is enough to kill you so "probably impossible" is generous here

          3 replies 4 retweets 58 likes
          Show this thread
        18. Health Nerd‏Verified account @GidMK 3 Apr 2018

          Final note: this thread doesn't talk about skin exposure to acrylamide, which is different. But unless people are rubbing thousands of cups of coffee on their skin each day, I reckon we're alright there too

          4 replies 6 retweets 61 likes
          Show this thread
        19. End of conversation

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