HPV vaccine has an excellent safety profile as demonstrated by best evidence http://bmcinfectdis.biomedcentral.com/articles/10.1186/1471-2334-11-13 … https://twitter.com/itsmepanda1/status/747129530192658432 …
Different vaccines have different safety profiles as they are, as you've identified, different procedures.
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Paracetamol generally safe for pregnancy, oxycodone not so much, as an example.
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