Any early intervention with proven safety and at least some positive data should be absolutely recommended, preferably when that intervention is widely accessible and/or patent-free rather than just doing nothing. Risk mitigation. Let doctors doctor.
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Not all of EBM is contained in RCTs. EBM is the intersection of patient needs, doctors clinical appraisal and experience, AND best available science.
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Replying to @GabinJean3 @GidMK
Are you advocating for Ivermectin to treat breakthrough infections after vaccination, or instead of vaccination?
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Replying to @GainOfDystopia @GidMK
ivermectin and vaccines seem like a good combination for most scenarios except for those that are more at risk from the vaccine than the disease (say, under 30s with no comorbidities), but IVM has more use cases, like post-exposure prophy, treatment.
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Replying to @GabinJean3 @GidMK
The risk of Covid for under 30s is much greater than the risk of vaccines. Death is not the only bad outcome. https://www.timesofisrael.com/more-than-10-of-israeli-kids-who-got-virus-now-suffer-from-long-covid-study/ …pic.twitter.com/04H3TZsN6z
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Replying to @GainOfDystopia @GidMK
Would the results be the same if you compared deaths and hospitalizations due to all causes, not just myocarditis, and took into account the fact that not all under 30s will actually catch covid? That's always an issue with such comparisons.
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Replying to @GabinJean3 @GidMK
The risk benefit calculation for vaccines isn’t even close.https://www.timesofisrael.com/more-than-10-of-israeli-kids-who-got-virus-now-suffer-from-long-covid-study/ …
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Replying to @GainOfDystopia @GidMK
I'm sorry but you're gonna need to send us data, not just press articles. For instance in 0-17 years old flu kills more than COVID, but covid vax kills more than flu shots. By a 1 to 2 orders of magnitude.https://trialsitenews.com/covid-19-vaccinations-98-times-more-deadly-than-flu-vaccines-according-to-vaers-reports/ …
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Replying to @GabinJean3 @GainOfDystopia
That is total nonsense. Displays a very basic misunderstanding of the reporting systems, data collection, etc
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Replying to @GidMK @GainOfDystopia
Of course, no causality is clearly established there and the confidence interval is very wide. But given the magnitude of the signal, good luck finding an alternative explanation.
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Oh, there are numerous alternative explanations. The first, and most obvious, has to do with how voluntary reporting systems work. It's why anyone who has even the most basic understanding of VAERS would never write such absolute nonsense
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