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GidMK's profile
Health Nerd
Health Nerd
Health Nerd
Verified account
@GidMK

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Health NerdVerified account

@GidMK

Epidemiologist. Writer (Guardian, Observer etc). "Well known research trouble-maker". PhDing at @UoW Host of @senscipod Email gidmk.healthnerd@gmail.com he/him

Sydney, New South Wales
theguardian.com/profile/gideon…
Joined November 2015

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    1. Health Nerd‏Verified account @GidMK Sep 6

      This study is a common citation of ivermectin believers, has been reported widely, and I think is a great teaching tool in how little effort it takes to be critical about research findings 1/npic.twitter.com/YDZNB1JP5R

      19 replies 279 retweets 881 likes
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    2. Health Nerd‏Verified account @GidMK Sep 6

      2/n The study is here, and has an objectively large impact with nearly a dozen news stories and an Altmetric of 2750https://www.medrxiv.org/content/10.1101/2021.05.31.21258081v1 …

      1 reply 7 retweets 76 likes
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    3. Health Nerd‏Verified account @GidMK Sep 6

      3/n The study is pretty simple - 116 people with Covid-19, randomized to either receive ivermectin or a placebo Reported results were viral load, and more specifically proportion of people with Ct>30 at various time points on PCRpic.twitter.com/ozXyxZwAOj

      2 replies 6 retweets 75 likes
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    4. Health Nerd‏Verified account @GidMK Sep 6

      4/n The authors report a marginally significant benefit at various days using an uncorrected logistic regression, and from this the massive attention sprangpic.twitter.com/5xk5vLDkrH

      2 replies 7 retweets 78 likes
      Show this thread
    5. David Boulware, MD MPH‏Verified account @boulware_dr Sep 7
      Replying to @GidMK

      This is a really simplistic analysis. As longitudinal repeated measures, a mixed regression model would be better (or alternatively linear regression) to look at change over time. Change over time eliminates picking arbitrary (?post-hoc) thresholds for endpoint or exclusion.

      2 replies 1 retweet 2 likes
      Health Nerd‏Verified account @GidMK Sep 7
      Replying to @boulware_dr

      Also a very good point! I genuinely do not understand why their main analysis would be simple logistic regressions repeated at different time points. They do have a K-M curve there which is at least more useful

      4:27 AM - 7 Sep 2021
      • 1 Like
      • David Boulware, MD MPH
      1 reply 0 retweets 1 like
        1. Health Nerd‏Verified account @GidMK Sep 7
          Replying to @GidMK @boulware_dr

          And even the K-M curve is adjusted to symptomatic onset and only done for symptomatic patients?pic.twitter.com/RJMPSDmMTi

          0 replies 0 retweets 1 like
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