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GidMK's profile
Health Nerd
Health Nerd
Health Nerd
Verified account
@GidMK

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Health NerdVerified account

@GidMK

Epidemiologist. Writer (Guardian, Observer etc). "Well known research trouble-maker". PhDing at @UoW Host of @senscipod Email gidmk.healthnerd@gmail.com he/him

Sydney, New South Wales
theguardian.com/profile/gideon…
Joined November 2015

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    1. WesElyMD‏Verified account @WesElyMD Sep 1

      1/🧵💥 NEW COVID THERAPY SAVES LIVES Adding baricitinib to steroids will save 1,000s of hospitalized #COVID pts. Our @LancetRespirMed COV-Barrier study is FREE. I explain👇why it’s such a great #Pandemic discovery story: a new way to ⬇️ COVID19 deaths. https://bit.ly/3DE8Co8 pic.twitter.com/6KcfQrljqC

      ISICEM, Vince Marconi, Giuseppe Citerio and 4 others
      1. ISICEM @ISICEM

      2. Vince Marconi @vmarconi2

      3. Giuseppe Citerio @Dr_Cit

      4. Joanna Stollings @JoannaCCPharmD

      5. LillyPad EU @LillyPadEU

      6. Eli Lilly and Company @LillyPad

      7. Francis S. Collins @NIHDirector

      70 replies 669 retweets 1,388 likes
      Show this thread
    2. Kramer‏ @KramerTheLab Sep 1
      Replying to @WesElyMD @LancetRespirMed and

      @GidMK @K_Sheldrick you know what to do 😂

      1 reply 0 retweets 2 likes
    3. Kyle Sheldrick‏ @K_Sheldrick Sep 1
      Replying to @KramerTheLab @WesElyMD and

      I have a few thoughts, the first is that this looks quite legitimate to me. The increases in sample size aren't inappropriate if they were based on a lower than expected event rate on unblinded data. 1/

      1 reply 0 retweets 2 likes
    4. Kyle Sheldrick‏ @K_Sheldrick Sep 1
      Replying to @K_Sheldrick @KramerTheLab and

      Usually I'm a hard arse on unexamined for secondary outcomes where primary outcomes not significant... but come on it's "all cause mortality" not "oxygen requirements for males 40-59 admitted on a Tuesday" I would be loathe to dismiss that for purist FWER control! 2/

      2 replies 0 retweets 4 likes
    5. Kyle Sheldrick‏ @K_Sheldrick Sep 1
      Replying to @K_Sheldrick @KramerTheLab and

      The data presented are all reasonable and derivable from the method described. The research described seems plausible for the resources involved and timelines described. 3/

      1 reply 0 retweets 2 likes
    6. Kyle Sheldrick‏ @K_Sheldrick Sep 1
      Replying to @K_Sheldrick @KramerTheLab and

      To be honest, my index of suspicion that there is dodginess here is very low. I can't really see any red flags at all for fraud or research malpractice in the paper. 4/

      2 replies 0 retweets 2 likes
    7. Health Nerd‏Verified account @GidMK Sep 1
      Replying to @K_Sheldrick @KramerTheLab and

      Agreed. Whether the difference in mortality is a real effect or (unlikely) a statistical quirk is perhaps questionable given that disease progression appeared to be pretty similar between groups

      1 reply 0 retweets 0 likes
    8. Health Nerd‏Verified account @GidMK Sep 1
      Replying to @GidMK @K_Sheldrick and

      That being said, the study itself has no red flags I can immediately identify, looks to be a really well-done and transparent piece of research, and the benefit is quite consistent across various secondary analyses. Pretty convincing stuff!

      2 replies 0 retweets 2 likes
    9. Health Nerd‏Verified account @GidMK Sep 1
      Replying to @GidMK @K_Sheldrick and

      Granted, this is in extremely unwell people (~30% risk of death), but it's still quite an encouraging result and the trial itself seems on the level

      1 reply 0 retweets 3 likes
      Health Nerd‏Verified account @GidMK Sep 1
      Replying to @GidMK @K_Sheldrick and

      Oh, and one final point - while there are numerous issues with pharmaceutical company funded research, I've yet to see an obviously fraudulent paper funded by pharma. They may do dodgy things with data, but they're MUCH sneakier about it than the ivermectin fakes

      6:19 PM - 1 Sep 2021
      • 1 Retweet
      • 4 Likes
      • Kieron Drake Evelyn K theo Shaun Lehmann Chomes
      3 replies 1 retweet 4 likes
        1. New conversation
        2. Shaun Lehmann‏ @shaun_lehmann Sep 1
          Replying to @GidMK @K_Sheldrick and

          Did you see that an ivermectin overdose turned up at a hospital in Sydney?

          1 reply 0 retweets 1 like
        3. Health Nerd‏Verified account @GidMK Sep 1
          Replying to @shaun_lehmann @K_Sheldrick and

          Yes. Extremely concerning

          0 replies 0 retweets 2 likes
        4. End of conversation
        1. Atomsk's Sanakan‏ @AtomsksSanakan Sep 1
          Replying to @GidMK @K_Sheldrick and

          FYI: The MOA is fine, and just what one would predict would work.

          0 replies 0 retweets 4 likes
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        1. Thurstone Moar III‏ @ThurstoneMOAR Sep 1
          Replying to @GidMK @K_Sheldrick and

          Data faking is gonna be a proper job soon.

          0 replies 0 retweets 0 likes
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