No. I'm saying that there are numerous studies with positive results that you have not criticized for these exact same "flaws"
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Replying to @alexandrosM
Then the Niaee study has the same conjunction. In addition, they gave lower doses of ivermectin. And it is the only RCT to show any statistically significant improvement in mortality for ivermectin
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Replying to @GidMK @alexandrosM
To put it another way - there's no reasonable argument that in one study a similar regimen resulted in 80% improvement in mortality but in another it's a "flaw" when it resulted in no improvement in mortality. Either it is or isn't an issue
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Replying to @GidMK
I will remind you that I have said nothing about any other study. I've only written about the TOGETHER study. Everything else you ascribe to me is... strange?
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Replying to @alexandrosM
Precisely my point. This is the same regimen that other studies that found a benefit used. So why are you only critiquing the Together trial for this reason? If we were to discard evidence that used this regimen, there's no RCTs that indicate a benefit for ivermectin
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Replying to @GidMK
Ok, so looking at the Niaee trial now. Can you confirm if I have these facts right? - Ivermectin is combined with HCQ, Heparin, Oxygen - It's a trial that happened in June/July 2020pic.twitter.com/0JoyBCBKUh
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Replying to @alexandrosM
Yep! And found a mortality reduction of ~70% in favour of ivermectin. Indeed, the ~only~ RCT to have found such a statistically significant benefit
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Replying to @GidMK
But why do you say that the protocols were "the same" or "similar", since several other interventions were involved?
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Replying to @alexandrosM
Because the things that you are saying are an issue for Together were the same - ivermectin dosage, timing etc, although to be fair Together gave a higher dose to most participants
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Also worth noting that these were the same between groups, so you would not expect a differential effect. If your criticisms apply to Together, they should also apply to Niaee
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