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GidMK's profile
Health Nerd
Health Nerd
Health Nerd
Verified account
@GidMK

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Health NerdVerified account

@GidMK

Epidemiologist. Writer (Guardian, Observer etc). "Well known research trouble-maker". PhDing at @UoW Host of @senscipod Email gidmk.healthnerd@gmail.com he/him

Sydney, New South Wales
theguardian.com/profile/gideon…
Joined November 2015

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    1. Dr. Eric Osgood MD‏ @EdoajoEric Aug 24
      Replying to @GidMK @K_Sheldrick @VaxScan

      Interesting, I havent gotten death threats but I am apparently going to be sentenced at the next Nuremberg trial for promoting experimental gene therapy. But also im going to jail bc Ive discussed that i believe ivermectin will ultimately be shown 2 have a + effect size in covid

      3 replies 0 retweets 11 likes
    2. Dr. Eric Osgood MD‏ @EdoajoEric Aug 24
      Replying to @EdoajoEric @GidMK and

      It doesnt matter that mRNA doesnt interact with the genome and represents the safest vaccine vector, or that low certainty data and clinician judgement routinely guide practice.

      3 replies 0 retweets 7 likes
    3. Health Nerd‏Verified account @GidMK Aug 24
      Replying to @EdoajoEric @K_Sheldrick @VaxScan

      I think a worthwhile point to make there though is whether low quality data *should* guide clinical practice. For every success story there are half a dozen treatments proven ultimately ineffective

      2 replies 1 retweet 10 likes
    4. Dr. Eric Osgood MD‏ @EdoajoEric Aug 24
      Replying to @GidMK @K_Sheldrick @VaxScan

      The best evidence available should guide practice.

      3 replies 0 retweets 6 likes
    5. Health Nerd‏Verified account @GidMK Aug 24
      Replying to @EdoajoEric @K_Sheldrick @VaxScan

      And if the best evidence available cannot exclude serious harm from the treatment?

      1 reply 0 retweets 6 likes
    6. Kyle Sheldrick‏ @K_Sheldrick Aug 24
      Replying to @GidMK @EdoajoEric @VaxScan

      Then it comes down to a risk of serious harm vs a risk of serious benefit. E.g. many treatment options for some cancers are known to definitely cause harm, but the groups are small enough we can't be certain of benefit.

      2 replies 0 retweets 4 likes
    7. Health Nerd‏Verified account @GidMK Aug 24
      Replying to @K_Sheldrick @EdoajoEric @VaxScan

      But surely in that context a treatment should only be used within a pretty structured modality, with explicit consent etc? As a patient I'd be really worried if I was at potential harm and it wasn't clearly outlined

      1 reply 0 retweets 4 likes
    8. Kyle Sheldrick‏ @K_Sheldrick Aug 24
      Replying to @GidMK @EdoajoEric @VaxScan

      Oh yeah I completely agree with that, can't pretend to be more certain than you are, can't hide potential harm, can't override autonomy. That being said... 1/

      1 reply 0 retweets 3 likes
    9. Kyle Sheldrick‏ @K_Sheldrick Aug 24
      Replying to @K_Sheldrick @GidMK and

      If point estimate for drug x for covid is 20% relative reduction in mortality, but 95% CI crosses 1, and we decline to prescribed. Then with more studies the CI tightens and point estimate doesn't change. Now clear it works 100 million patients not treated. 2/

      1 reply 0 retweets 9 likes
    10. Kyle Sheldrick‏ @K_Sheldrick Aug 24
      Replying to @K_Sheldrick @GidMK and

      Do we have moral culpability for those that died that would have survived? I'm not sure there is such a huge difference between harm caused and harm not prevented. Waiting for more info is still an active decision not to treat. 3/3

      2 replies 0 retweets 9 likes
      Health Nerd‏Verified account @GidMK Aug 24
      Replying to @K_Sheldrick @EdoajoEric @VaxScan

      But the converse is also extremely problematic - HCQ we justified based on similar arguments and it appears to cause modest increases in death rates from covid. If the end result is a treatment that does cause harm, what is the moral culpability?

      10:31 PM - 24 Aug 2021
      • 3 Likes
      • Lars Mølgaard Saxhaug Kyle Sheldrick Brett Lombardi
      5 replies 0 retweets 3 likes
        1. New conversation
        2. Kyle Sheldrick‏ @K_Sheldrick Aug 24
          Replying to @GidMK @EdoajoEric @VaxScan

          High. Treatment decisions aren't no-risk. There's the argument about harms from drink driving vs punishment (moral culpability) too. 1/

          1 reply 0 retweets 2 likes
        3. Kyle Sheldrick‏ @K_Sheldrick Aug 24
          Replying to @K_Sheldrick @GidMK and

          Like in Australia if you speed drunk through a red light and there's nobody crossing the road you'll get your licence suspended. If a pedestrian happened to be there you get 10 years jail. I think this is wrong, there's no difference in the risks taken, just luck 2/

          1 reply 0 retweets 0 likes
        4. Show replies
        1. New conversation
        2. Dr. Eric Osgood MD‏ @EdoajoEric Aug 24
          Replying to @GidMK @K_Sheldrick @VaxScan

          We cant allow "but HCQ..." to be the harbinger of therapeutic nihilism.

          3 replies 0 retweets 4 likes
        3. Dr. Eric Osgood MD‏ @EdoajoEric Aug 24
          Replying to @EdoajoEric @GidMK and

          On the other hand there's "but methylprednisolone/dexamethasone." Based on the numbers needed to treat re: in hospital mortality, how many died awaiting physicians to accumulate a gigantic trial to spoonfeed them a conclusion their pathophys/pharm reasoning should have told them.

          1 reply 0 retweets 6 likes
        4. Show replies
        1. Brett Lombardi‏ @LombardiBrett Aug 24
          Replying to @GidMK @K_Sheldrick and

          What's the moral culpability of saying something "doesn't work" or "has no effect" when it causes modest increases in death? What about saying not airborne or doesn't transmit human-to-human? Underfunding TTI? Setting high bar for vaccine adverse events while 'using' lockdowns?!

          0 replies 0 retweets 0 likes
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        2. 𝑔𝒶𝒾𝓃𝓈 𝒻𝓇𝑜𝓂 𝒹𝒾𝓈𝑜𝓇𝒹𝑒𝓇‏ @Dahuuu Aug 25
          Replying to @GidMK @K_Sheldrick and

          It's quite puzzling to me after all this time you still don't seem to be aware all of the harm reported from HCQ was from late-stage, overdosed trials (Solidarity, Recovery)

          1 reply 0 retweets 0 likes
        3. AlistairTN‏ @TnAlistair Aug 25
          Replying to @Dahuuu @GidMK and

          It pretty much says it all about medical research evaluation that the Oxford HCQ trials still stand. It's a much bigger problem than small fraudulent ivermectin studies but hey, we have to have priorities.

          1 reply 0 retweets 2 likes
        4. Show replies

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