Once upon a time, physicians used clinical judgement and prescribed, and professional medical societies gave conditional recommendations for, interventions based on low or sometimes very low certainty data. No one called them miracles or referred to them by their veterinary use.
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I reckon there are quite a few fraudulent studies that we'll never know are fake because no one is actually incentivised to do this work and the only payment you get is hate mail, death threats, and internet randoms accusing you of working for the pharmaceutical industry
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Yep. There's also the fact some fraud is genuinely undetectable. There's a ppt from the FDA in 2001 called "The F word", they went back and looked at whistleblower-disclosed fabrication and even knowing it was fraud still couldn't find red flags in the data in many cases.
End of conversation
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