This one feel free to have a look yourself:https://www.cureus.com/articles/50511-early-antiandrogen-therapy-with-dutasteride-reduces-viral-shedding-inflammatory-responses-and-time-to-remission-in-males-with-covid-19-a-randomized-double-blind-placebo-controlled-interventional-trial-eat-duta-androcov-trial---biochemical …
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It looks like the authors have mislabeled table 1, but the other tables I can't even explain. These percentages, for example, aren't possible for any values between 40-45 as far as I can tellpic.twitter.com/qbsP3iUHM0
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The whole thing is just...very odd. The p-values are also bizarre - I get a chi-squared p-value of 0.0005, not 0.036, for the last line
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Health Nerd Retweeted Health Nerd
For those wondering what I mean when I say "impossible"https://twitter.com/GidMK/status/1428174111834923018?s=20 …
Health Nerd added,
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Worth noting that lots of papers have one or two impossible values - often there is a person missing from one line in a table, that throws off the percentages. It's not ideal, but it's a very simple mistake It becomes worrying when this mistake is repeated a lot
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Replying to @GidMK
There is something else that struck me... How in the heck did they get "pre-COVID" data for CSR, ESR??? I did look at the recruitment chain and there isn't any way they have that honestly. Outside of imperfectly 'perfect' numbers there's some other oddities. What am I missing?
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Replying to @GidMK
People don't get CRP/ESR as part of normal diagnostics. Looking at the list of pre-morbid conditions none have a reason to have had a CRP/ESR regularly. To me it smells like data manufacturing...
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Replying to @ThaumaturgeRN @GidMK
The TL/DR is these are uncommon tests, done only when someone is sick and the suspect is immune response. Nobody 'baselines' CRP/ESR.
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Replying to @ThaumaturgeRN @GidMK
We had notice the inconsistency- for example, 5/44 and 24/44 patients were the numbers
@GidMK brought - that will be corrected soon. We will submit the primary findings of the trial shortly. Please let us know in case of other inconsistencies preferably in a constructive manner.1 reply 0 retweets 1 like
Thus far, every percentage I have checked is incorrect or impossible in the tables of the study. So if you are going to correct the paper I'd start with all of the percentages
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Replying to @GidMK @ThaumaturgeRN
We’re performing a thorough analysis for a single version of all corrections. In this correction we will also provide the dataset.
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There are other inconsistencies as well that we will correct. We’re not a huge group and we got massive amounts of work - we’d love to get help in terms of reviewing, checking, etc, the data.
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