Summary results for ivermectin for COVID-19 from the large TOGETHER trial were just released No benefit whatsoever for ivermectin on risk of hospitalization or mortality in a mild outpatient grouppic.twitter.com/5eZj0pc5V6
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Did all of this conjecture about ivermectin stem from one computer model that indicated ivermectin bonds to covid proteins? How did this happen? Who is benefiting from this?
3rd promising result for fluvoxamine - I agree, encouraging as outpt Rx; eager to see more data. Prior small RCT (0/80 worsened, vs 6/72 placebo): https://jamanetwork.com/journals/jama/fullarticle/2773108 … & prospective cohort (opt-in to Rx after exposure; 0/65 hosp, vs 6/48 placebo):https://academic.oup.com/ofid/article/8/2/ofab050/6124100 …
It's very intriguing but honestly I don't feel great about it given the tiny sample sizes. The relative silver lining of this current wave with the delta variant though is that we might actually get large numbers to know which medications are and aren't efficacious
Pardon? Fluvoxamine, as in Luvox, as in SSRI anti-depressant? Bizarre, yet interesting news, must be in relation to its anti-inflam effects, am guessing. Its generic now in Canada, so not too expensive of an option, wondering what price per pill in US is, though.
Yes, how on earth did anyone decide to study that one out of all the drugs out there? Well, whoever it was, if it pans out good on them but I'd love to know the logic behind it.
fluvoxamine the anti-depressant?
Where did the fluvoxamine data come from?
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