Summary results for ivermectin for COVID-19 from the large TOGETHER trial were just released No benefit whatsoever for ivermectin on risk of hospitalization or mortality in a mild outpatient grouppic.twitter.com/5eZj0pc5V6
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In other words, it's still possible ivermectin helps a bit, but it is very unlikely that it is a "miracle drug" that everyone should be taking at this point
TOGETHER is the largest, most well-conducted ivermectin study to date, and it was in low-risk outpatients Which means the two main arguments from the ivermectin proponents simply no longer make any sense at all
Also, people are talking about minor dosing differences (0.4mcg/kg vs 0.6mcg/kg) as if that's meaningful which is HILARIOUS because the dosage used in TOGETHER is higher than most of the studies showing massive mortality benefits
One more point - there DOES appear to be a benefit in these slides from fluvoxamine for hospitalization/ED. I don't know enough about the literature on fluvoxamine to comment, but this looks very encouraging in isolationpic.twitter.com/X7Z1RjEZhL
I wouldn’t, given the really low prior probability for #Ivermectin to work against #COVID19 based on the very high concentration required for antiviral activity, several times higher than what can be safely achieved in humans.
Basically, #Ivermectin is the parrot in a certain @montypython sketch. It’s not pining for the fjords. It’s dead.pic.twitter.com/aunXyCLNWu
that's about the same benefit as public mask usage, 10 to 15%. Yet they are pushed, as a little is better than nothing.https://swprs.org/face-masks-evidence/ …
Why would we expect Ivm to work 14 days after symptoms. Shouldn't antivirals be taken early in the infection?
They have them ivm for just three days Weird
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