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GidMK's profile
Health Nerd
Health Nerd
Health Nerd
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@GidMK

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Health NerdVerified account

@GidMK

Epidemiologist. Writer (Guardian, Observer etc). "Well known research trouble-maker". PhDing at @UoW Host of @senscipod Email gidmk.healthnerd@gmail.com he/him

Sydney, New South Wales
theguardian.com/profile/gideon…
Joined November 2015

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    1. Health Nerd‏Verified account @GidMK Aug 10

      2/n The paper is here, and as with all such reviews is a collation of the thoughts of the authors backed up by references they believe support the case:https://www.sciencedirect.com/science/article/pii/S2052297521000883 …

      1 reply 7 retweets 64 likes
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    2. Health Nerd‏Verified account @GidMK Aug 10

      3/n At the outset, I find the introduction and title very odd. Ivermectin has been honored by the Nobel committee for an ~entirely different purpose~ Other treatments that received Nobels include: - lobotomy - giving people malariapic.twitter.com/fBW4BWfk5P

      4 replies 12 retweets 153 likes
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    3. Health Nerd‏Verified account @GidMK Aug 10

      4/n So it's an odd start, but overall I think the biggest weakness of this review is the issue with most reviews - the studies it relies on

      1 reply 4 retweets 75 likes
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    4. Health Nerd‏Verified account @GidMK Aug 10

      5/n Firstly, the review cites the retracted and potentially fraudulent Elgazzar paper a number of times - in the abstract, and then at least twice in the discussion of RCTspic.twitter.com/xEAWEDSJri

      1 reply 9 retweets 115 likes
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    5. Health Nerd‏Verified account @GidMK Aug 10

      6/n The review also talks about meta-analyses of RCTs for ivermectin, but as I've discussed when excluding the retracted Elgazzar study the results of these analyses look very different!pic.twitter.com/QzQAUS9Kk0

      1 reply 3 retweets 87 likes
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    6. Health Nerd‏Verified account @GidMK Aug 10

      Health Nerd Retweeted Health Nerd

      6.5/n One of the reviews that they cite as positive is being retracted and corrected due to the potential fraud in the literature as we speakhttps://twitter.com/GidMK/status/1425242452974133251?s=20 …

      Health Nerd added,

      Health NerdVerified account @GidMK
      This is a fantastic display of scientific integrity - very much respect for @DrAndrewHill and team https://retractionwatch.com/2021/08/10/ivermectin-meta-analysis-to-be-retracted-revised-say-authors/#more-122837 …
      Show this thread
      1 reply 6 retweets 104 likes
      Show this thread
    7. Health Nerd‏Verified account @GidMK Aug 10

      7/n Moreover, they reference "Cochrane analysis methodology" but fail to note that the Cochrane Collaboration has just published a review that: 1) found no benefit for ivermectin 2) pointed out that these reviews didn't actually use "Cochrane methodology"pic.twitter.com/WAG99U6LJW

      1 reply 14 retweets 146 likes
      Show this thread
    8. Health Nerd‏Verified account @GidMK Aug 10

      8/n The review then moves on to argue that an observational analysis of Peru shows enormous benefits for ivermectin. I've talked about this ecological paper before, and why I think it is not very useful as evidence https://twitter.com/GidMK/status/1424525769242406915?s=20 …pic.twitter.com/isiLIa4SgL

      1 reply 3 retweets 66 likes
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    9. Health Nerd‏Verified account @GidMK Aug 10

      9/n If nothing else, the graph in the paper is misleading - Peru officially authorized the use of ivermectin on May 5th 2020 and started distributing it en mass shortly afterpic.twitter.com/O3Xhq8RSTf

      4 replies 2 retweets 59 likes
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    10. Health Nerd‏Verified account @GidMK Aug 10

      10/n The review also briefly discusses the biological plausibility of ivermectin use. This is pretty meagre, but the 2 studies cited don't seem to be terriblepic.twitter.com/VDkTQdS5bF

      5 replies 2 retweets 52 likes
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      Health Nerd‏Verified account @GidMK Aug 10

      11/n Some of the issues above are definitely not the fault of the authors - for example, the Cochrane review came out after this paper had already been accepted - but they do make me disagree entirely with the conclusions of the paper

      8:26 PM - 10 Aug 2021
      • 3 Retweets
      • 60 Likes
      • Yasir Sultani Greg Gransden Chris Richards 🐬🖖🏻 #ClassWarNotColdWar literally lizard, seekmaking truthsenser 𝔾𝕚𝕧𝕖 𝕚𝕥 𝕦𝕡... 𝕊𝕙𝕒𝕣𝕖 𝕚𝕥 𝕠𝕦𝕥... ilovechocolat Sol Saturn Mathematiker plädiert für Ruhe und Rationalität Erik Kohl
      1 reply 3 retweets 60 likes
        1. Health Nerd‏Verified account @GidMK Aug 10

          12/n I think that the Cochrane review into ivermectin remains solidly the best evidence around, arguing that we should only be using the drug in the context of a clinical trial until we have better evidencepic.twitter.com/PA5h7p5pTg

          11 replies 14 retweets 140 likes
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