Uh, that's not AZ and it's also not a criticism of the trial at all. I'm very confused
Tbh, that's more of a subjective assessment - they were some of the biggest ever, but 'best' is just my opinion. Given how many variables are involved in high-quality trials (literally 100s of pages of protocol), comparing them is a very time-consuming process
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Understood. What do you mean they had strict enrollment criteria to reduce bias? Doesn’t it make the trial more biased if you are only testing a narrow segment of the population?
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Nope, it makes it potentially less generalisable. Bias is issues that effect the results, generalisability is whether the results can be applied to populations outside of your trial
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