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GidMK's profile
Health Nerd
Health Nerd
Health Nerd
Verified account
@GidMK

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Health NerdVerified account

@GidMK

Epidemiologist. Writer (Guardian, Observer etc). "Well known research trouble-maker". PhDing at @UoW Host of @senscipod Email gidmk.healthnerd@gmail.com he/him

Sydney, New South Wales
theguardian.com/profile/gideon…
Joined November 2015

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    1. Covid19Crusher‏ @Covid19Crusher Aug 8

      The large (n=3,532), prospective, controlled, Indian study of Ivermectin as a pre-exposure prophylaxis of healthcare workers is now peer-reviewed and published. https://www.cureus.com/articles/64807-prophylactic-role-of-ivermectin-in-severe-acute-respiratory-syndrome-coronavirus-2-infection-among-healthcare-workers#comments …pic.twitter.com/hpszcZGfhw

      105 replies 1,849 retweets 3,146 likes
      Show this thread
    2. Matt Ives‏ @Matthew_Ives Aug 8
      Replying to @Covid19Crusher

      @ydeigin is this study any good?

      6 replies 1 retweet 4 likes
    3. Yuri Deigin‏ @ydeigin Aug 8
      Replying to @Matthew_Ives @Covid19Crusher

      I dunno, haven’t looked but just the conclusion seems like a huge stretch: 2 doses resulting in a protective effect for a month?? And 83% efficacy for a month is shit: vaccines provide 95% for months. @GidMK @K_Sheldrick did you guys look at the Indian study above by any chance?

      54 replies 3 retweets 21 likes
    4. Kyle Sheldrick‏ @K_Sheldrick Aug 8
      Replying to @ydeigin @Matthew_Ives and

      I read it and don't really understand many of the key parts of it to be honest, why was it ethical to run an interventional trial of an experimental drug but not ethical to randomise? There are also lots of things missing we'd expect to see in a trial like this.

      4 replies 2 retweets 13 likes
    5. StephenMills‏ @Stephengm99 Aug 8
      Replying to @K_Sheldrick @ydeigin and

      It’s not RCT. It didn’t test asymptomatic or “those who chose not to be tested”. How bad is that?

      2 replies 1 retweet 4 likes
    6. Kyle Sheldrick‏ @K_Sheldrick Aug 8
      Replying to @Stephengm99 @ydeigin and

      It's definitely an issue (especially bias in the likely correlation between risk taking behaviour and participations), but the effect size is enormous and if the data are real hard to see it arise from those biases alone.

      3 replies 0 retweets 3 likes
    7. Health Nerd‏Verified account @GidMK Aug 8
      Replying to @K_Sheldrick @Stephengm99 and

      I don't agree tbh - non-randomized trial with no blinding of outcome assessment (people chose to get a PCR test or not) and no real correction for exposure at baseline at all. Hard to know what the results mean, but they ~could~ be massively biased

      3 replies 0 retweets 7 likes
    8. Kyle Sheldrick‏ @K_Sheldrick Aug 8
      Replying to @GidMK @Stephengm99 and

      Look, I think that's a completely reasonable position too.

      1 reply 0 retweets 3 likes
      Health Nerd‏Verified account @GidMK Aug 8
      Replying to @K_Sheldrick @Stephengm99 and

      I will say that the idea that it is unethical to run an RCT is bizarre to me. If you believe that ivermectin is effective, having a control group is unethical random or no. If you don't know whether it's effective, an RCT is ethical

      5:49 PM - 8 Aug 2021
      • 1 Retweet
      • 6 Likes
      • Chris Street, 🇬🇧 MBA, MSc (Medicinal Chemistry) Aline Magalhaes, MD Kyle Sheldrick Tak Jose Gallucci-Neto ZaneBarb
      1 reply 1 retweet 6 likes

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