Cochrane review on ivermectin just dropped. This is the current gold-standard summary: "the reliable evidence available does not support the use ivermectin for treatment or prevention of COVID‐19 outside of well‐designed randomized trials." https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD015017.pub2/full …
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Another interesting point - the Cochrane review authors addressed why their review disagrees with previous very positive studies on ivermectin. They were particularly pointed about the weird ivmmeta websitepic.twitter.com/BjTqfxf9h8
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Have you seen this
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But doesn't all the previous use of ivermectin for treting other conditions include safety studies?
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It is surprising to me how many people in medicine were so quick to accept that hydroxychloroquine and/or ivermectin were effective treatments for viral infection when the history of antiviral meds is so disappointing. Low prior probability plus bad evidence should = no use.
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Review result =
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Do we have examples where something like this has happened, and it’s ended up being a strong positive result in future? Or does the equivocal data point towards low or no effect?
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It’s not likely in this case. There aren’t a lot of new or additional studies underway but the results are very inconsistent, which is a bad sign for detecting a conclusive, sizable effect
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Pretty sure IVM is going to fall into the (undetectable) small benefit/detriment, I.e. no effect category.
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“or ending them”? Saying nothing about IVM’s efficacy w/r/t Covid...is there any evidence for such a serious claim as this?
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Cochrane review finds Ivermectin not recommended for use outside of RCTs.
Please stop using worming tablets to treat virus infections folks...