Well, that sets up an interesting conflict between interests of the authors and the publishers!https://twitter.com/RetractionWatch/status/1414645877164158983 …
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IV embedded in RCT, "encouragement design" style. You don't have to prevent something from being uploaded to sci-hub, you just need something that makes it more likely (i.e. you upload them yourself). Interpretation issues would happen, but not an existential threat.
But scihub works by using general logins so anything that is uploaded to a journal (from my understanding) would get on there. I think the only way to do this would be to work WITH scihub, but that's going to be tough
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