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GidMK's profile
Health Nerd
Health Nerd
Health Nerd
Verified account
@GidMK

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Health NerdVerified account

@GidMK

Epidemiologist. Writer (Guardian, Observer etc). "Well known research trouble-maker". PhDing at @UoW Host of @senscipod Email gidmk.healthnerd@gmail.com he/him

Sydney, New South Wales
theguardian.com/profile/gideon…
Joined November 2015

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    1. Health Nerd‏Verified account @GidMK Jul 7
      Replying to @CJforeveryoung

      At this point, the studies aren't short! We've now got 10-12 months of data on side-effects from the large RCTs and safety information from 100s of millions of doses. While there are unknowns, they are fast shrinking

      1 reply 0 retweets 1 like
    2. CJ‏ @CJforeveryoung Jul 7
      Replying to @GidMK

      But with no controls groups left and weak passive reporting systems, I'm not sure this can be relied up as robust science. Can we compare a normal/standard vaccine trial to it in all honesty? Sorry, I've always questioned everything. Drove my mother crazy!

      1 reply 0 retweets 1 like
    3. Health Nerd‏Verified account @GidMK Jul 7
      Replying to @CJforeveryoung

      Not sure what you mean by no control groups - still plenty of people unvaccinated and trials are ongoing! And we definitely can compare, in most respects the Covid-19 vaccine trials were far better than your average trial

      1 reply 0 retweets 1 like
    4. CJ‏ @CJforeveryoung Jul 7
      Replying to @GidMK

      From what I've read the Oxford vaccine has unblinded for ethical reasons. But the adverse events part of the trial is being undertaken with no controls? Reliant on an antiquated reporting system that pre 2021 was largely ignored by the medical profession. Surely not reliable?

      1 reply 0 retweets 1 like
    5. Health Nerd‏Verified account @GidMK Jul 8
      Replying to @CJforeveryoung

      I'm not sure who told you that the reporting systems are antiquated or ignored but that is definitely untrue. Depends on where you live ofc, but in general they're extremely good at catching even very rare events that only happen once per 100k/million shots

      1 reply 0 retweets 0 likes
    6. CJ‏ @CJforeveryoung Jul 8
      Replying to @GidMK

      Can you prove that every doctor who is presented with a patient with issues after a vaccination reports it! From what I understand it's a lengthy process, often in a middle of a busy shift. I have two gp friends and neither knew about the yellow card system till last year.

      2 replies 0 retweets 1 like
    7. Health Nerd‏Verified account @GidMK Jul 8
      Replying to @CJforeveryoung

      That's part of the beauty of the system - they're designed to detect event the potential hint of an effect, so even if only a fraction of events are reported they are usually picked up. Very sensitive to any potential harm

      1 reply 0 retweets 0 likes
    8. CJ‏ @CJforeveryoung Jul 8
      Replying to @GidMK

      I wonder why the issues that have shown up weren't picked up in the actual trial? Is AZ being fully phased out in Australia now?

      1 reply 0 retweets 0 likes
    9. Health Nerd‏Verified account @GidMK Jul 8
      Replying to @CJforeveryoung

      Nope. The reason is that the events were too rare - trials are designed to pick up things that happen up to about once every 10,000 people, but a trial to pick up a 1 in a million event would have to include 10s of millions of people

      1 reply 0 retweets 0 likes
    10. CJ‏ @CJforeveryoung Jul 8
      Replying to @GidMK

      So blood clots and thrombotic events are 1 in a million after this vaccine?

      1 reply 0 retweets 0 likes
      Health Nerd‏Verified account @GidMK Jul 8
      Replying to @CJforeveryoung

      The incidence appears to vary somewhat but is around 1 in 100k. For that sort of rate, you'd need nearly 1 million people in the trial, which is about 50x bigger than the biggest trials of vaccines ever conducted (which were done for COVID-19 vaccines)

      1:59 AM - 8 Jul 2021
      1 reply 0 retweets 0 likes
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