Do child COVID vaccines merit blanket Emergency Use Authorization? With @sdbaral and @VPrasadMDMPH, we suggest the low COVID risk to children undercuts such a regulatory decision, and that accelerated mass child vaccination carries underappreciated risks.https://medium.com/@wpegden/covid-19-vaccines-in-children-6cdff15b2415?source=friends_link&sk=49487d63149fc87e859deedf0d577eba …
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I'm all for discussing risk vs benefit, but there does not appear to be much engagement with the risk from COVID-19 here at all. It is obviously non-zero for children, even if it is much lower than for adults
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Risk of death for 12-15yo is ~1 in 40-60,000 Risk of hospitalization is ~1 in 1,000(?) So vaccinating 1M 12-15yo could potentially prevent ~20 deaths and 1,000 hospitalizations? I see how we'd want a large trial sample to assess safety. I think the authors ask: is 1,131 enough?
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The article points out quite clearly that vaccinating children with preexisting conditions head a totally different risk benefit ratio. The risk for healthy children is more like 1-4 per million.
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Re: "Best evidence indicates a risk of death if infected from COVID-19 for 12-15 year olds of around 1 in 40-60,000, yet the article presents this as essentially no risk" Yup. 0.001% = ~1 in 100,000 0.003% = ~1 in 33,000 https://twitter.com/GidMK/status/1389725097368322049 … https://static-content.springer.com/esm/art%3A10.1007%2Fs10654-020-00698-1/MediaObjects/10654_2020_698_MOESM1_ESM.pdf …pic.twitter.com/bHCoiYq7ZH
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Re: "0.001% = ~1 in 100,000 0.003% = ~1 in 33,000" Greater risk of death than their GBS example: "In 1976, the vaccination campaign in anticipation of a deadly Swine flu (H1N1) [was] derailed by very rare cases of Guillain-Barré" https://medium.com/@wpegden/covid-19-vaccines-in-children-6cdff15b2415 … https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4599698/ …pic.twitter.com/7IXgPK7B5R
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Not acceptable. When did life become so cheap in Canada? It’s frightening.
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