Question for all the smart people who follow me: can you explain simply why the J&J vaccine only needs one dose but Pfizer/AZ/Moderna etc need 2?
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Full disclosure: someone asked me this and I have no idea so plz enlighten me because I'm sure the answer is super interesting but immunology is HARD
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Replying to @GidMK
Isn’t it because they got a decent antibody response with one dose and decided to roll the dice with a one dose trial. Others were more cautious.
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Replying to @scottrosenstein
Plausible, but I'm sure there's some immunological addition to that explanation
7:26 PM - 18 Mar 2021
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