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GidMK's profile
Health Nerd
Health Nerd
Health Nerd
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@GidMK

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Health NerdVerified account

@GidMK

Epidemiologist. Writer (Guardian, Observer etc). "Well known research trouble-maker". PhDing at @UoW Host of @senscipod Email gidmk.healthnerd@gmail.com he/him

Sydney, New South Wales
theguardian.com/profile/gideon…
Joined November 2015

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    1. Health Nerd‏Verified account @GidMK Feb 14

      21/n The study also wasn't pre-registered, which is an issue considering it started on March 1st 2020. When was the treatment protocol (HCQ+azithro and dexamethasone) decided on?pic.twitter.com/sRvMutWu9k

      1 reply 4 retweets 84 likes
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    2. Health Nerd‏Verified account @GidMK Feb 14

      22/n Also, how in the world did one relatively modest-sized hospital have 8 fully-dedicated COVID-19 wards open in Barcelona, at a time when Spain itself only had a handful of COVID-19 cases? Any Barcelonian followers who can elaborate?

      6 replies 5 retweets 97 likes
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    3. Health Nerd‏Verified account @GidMK Feb 14

      23/n The same author group wrote another paper on the same patient population in January. Why was there no mention of this trial, or the MASSIVE mortality reduction anywhere? None of this is necessarily disqualifying, it's just really odd!pic.twitter.com/n6J8ihD9S3

      1 reply 4 retweets 78 likes
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    4. Health Nerd‏Verified account @GidMK Feb 14

      24/n I should specify that none of this makes the study totally sketchy, it's just all really weird and they are things that the authors should have explained in the paper

      2 replies 2 retweets 58 likes
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    5. Health Nerd‏Verified account @GidMK Feb 14

      25/n Overall, what we have is a study that, if run as specified, was a non-randomized prospective cohort study that gives us very little/no new information on vitamin D for COVID-19

      2 replies 6 retweets 81 likes
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    6. Health Nerd‏Verified account @GidMK Feb 14

      26/n This doesn't mean that you shouldn't take vitamin D, it's relatively low-cost and the harm is mostly to your wallet, but the jury is still out whether it will have any benefit at all to COVID-19 🤷‍♂️

      10 replies 12 retweets 128 likes
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    7. Health Nerd‏Verified account @GidMK Feb 15

      27/n Update: the authors have confirmed that this was not a randomized trial on PubPeer. They are still using the word "random" in a very confusing way, but what is described here is not an RCT by any descriptionpic.twitter.com/epHN075OA7

      2 replies 6 retweets 47 likes
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    8. Health Nerd‏Verified account @GidMK Feb 15

      28/n And I wrote a piece about this trial and COVID-19 and vitamin D in generalhttps://gidmk.medium.com/vitamin-d-and-covid-19-an-update-59fb2f9cceb5 …

      5 replies 12 retweets 53 likes
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    9. Flâneur‏ @RadicalDiletta1 Feb 15
      Replying to @GidMK

      The Brazil study used a single dose of 200,000 IU (shown in numerous studies to be barely effective compared wityh daily dosage) - that raised the serum 25-hydroxyvitamin D levels a little - from poor to inadequate.

      1 reply 0 retweets 0 likes
    10. Health Nerd‏Verified account @GidMK Feb 15
      Replying to @RadicalDiletta1

      Like I said, it's hardly definitive, but it is the largest RCT done on the topic by far 🤷‍♂️

      1 reply 0 retweets 0 likes
      Health Nerd‏Verified account @GidMK Feb 15
      Replying to @GidMK @RadicalDiletta1

      Although that's also not true at all. Using a definition of 30ng/ml the supplementation decreased the rate of deficiency from 90% to 14%, so clearly it addressed deficiency if nothing else

      12:44 PM - 15 Feb 2021
      1 reply 0 retweets 0 likes
        1. Flâneur‏ @RadicalDiletta1 Feb 15
          Replying to @GidMK

          If you accept 30ng/ml as adequate, yes - but that figure isn't based on anything much at all, just one poor 1971 study. Many hunter-gatherers have been found to be regularly above 100, which makes the difference between 20 and 30 ng almost negligible.https://www.youtube.com/watch?v=QrU1yrmNIqc …

          0 replies 0 retweets 0 likes
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