What might explain the resurgence of COVID-19 in Manaus? New comment with @estercsabino @LewisBuss4 @nmrfaria and othershttps://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)00183-5/fulltext …
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One of the possible explanations, but P1 escape from neutralising antibody is maybe more important?
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Well, it wouldn't be the only serosurvey that has significantly overestimated the number of infections

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I think before the new wave I saw
@mgmgomes1 suggesting the sampling method was likely to cause overestimation. -
I've long been skeptical of the blood donor studies that often seem to find quite high estimates of seroprevalence
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How would it explain a *worse* 2nd wave though? Even if it was only 20%, it should be better, or at least the same as the first wave, right?
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