Would be consistent with the hypothesis that SARS-CoV-2 is just another coronavirus like HCoV-OC43 if the latter caused the pandemic of 1890-91. Reinfection of that certainly possible after 6-24 months and would only cause the common cold.
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Pretty much. Would be bad news for herd immunity, but otherwise not terrible
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It makes sense. My VERY limited knowledge of immunity seems to think a 2nd reinfection would trigger the memory B-cells to produce antibodies pretty quickly but not instantly. It's not sterilizing immunity, but I'll take prevention of serious disease.
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Well, in a while we’ll know well enough and we’ll say “well you’re right [wrong] of course”. Luna will smirk knowingly.
Thanks. Twitter will use this to make your timeline better. UndoUndo
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Or if the first infection was less severe.
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An asymptomatic/mild 1st infection would be less likely to be 'caught'. Not an immunologist but...wouldn't an asymptomatic/mild case also be more likely to NOT produce long lasting immunity?
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Just a thought. If asymptotic re-infection is more common than we realize AND the vaccine only prevents severe infection (not transmission), do we potentially have a vaccine that is ineffective at stopping this pandemic?
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It falls in to being as effective as the 2009 H1N1 vaccines, it downgrades it into a minor flu in which hospitals are better equipped to handle and can generally be dealt with via rest and some gatorade
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I have read that this is the natural course of action for most viral illnesses to the point that eventually the original virus is much less deadly, falling to the level of 'common cold'. I pray that occurs here. It seems the most optimistic hope given the level of infections
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Over thousands and years and also after selective pressure on the survival of the susceptible population of the infected species
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Reinfection in young, healthy individual despite development of antibody response following 1st infection. 2nd infection, 185 days earlier, was less severe. To confirm reinfection, genomes from both episodes sequenced & confirmed to belong to different SARS-CoV-2 clades