Oh look, something else to debunkpic.twitter.com/TYxJGfxGp0
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First off, I would start by just throwing out any observational study that isn't heavily controlled for potential confounds. Maybe keep ICON. That one was decent. Second, throw out anything with suspicious round numbers and suspiciously large claimed N.
I actually disagree with that claim, though. A single study can be fraudulent much, much more easily than a dozen of them can be. Yes, there are some soft endpoints, not a lot of placebos, many open-label studies, occasional vague reporting. Maybe focus on just mortality.
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