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GidMK's profile
Health Nerd
Health Nerd
Health Nerd
Verified account
@GidMK

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Health NerdVerified account

@GidMK

Epidemiologist. Writer (Guardian, Observer etc). "Well known research trouble-maker". PhDing at @UoW Host of @senscipod Email gidmk.healthnerd@gmail.com he/him

Sydney, New South Wales
theguardian.com/profile/gideon…
Joined November 2015

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    1. Health Nerd‏Verified account @GidMK 8 Dec 2020

      Interesting titbit from the Pfizer study - the attack rate in the general population and the people who had already had COVID-19 was similar. 1.3% of people who had COVID-19 antibodies BEFORE vaccination got infectedpic.twitter.com/c4rJ8TGQn5

      9 replies 35 retweets 146 likes
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      Health Nerd‏Verified account @GidMK 8 Dec 2020

      The main take-home from this is that people who have already had COVID-19 will probably benefit from vaccination, although it is interesting to note the high rate of 'reinfections' here (maybe people who were sick but asymptomatic at enrolment?)

      12:33 PM - 8 Dec 2020
      • 3 Retweets
      • 57 Likes
      • Bob Aziz🌌 Harry Hong ice9 epb41l2 Ketan Kurtadikar Eric Meyerowitz, MD Julia D Mahoney Faine Greenwood Anna van Bijnen
      9 replies 3 retweets 57 likes
        1. Health Nerd‏Verified account @GidMK 8 Dec 2020

          Worth noting that we need a lot more information on these individuals to make any firm statements - it's possible some were false +ves on serology, or that they were infected before the trial etc. Hard to tell from the information at hand!

          1 reply 1 retweet 22 likes
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        2. renacido‏ @LoneStarLivin 8 Dec 2020
          Replying to @GidMK

          any thoughts on those of us who have/had covid months ago and still have symptoms?

          1 reply 0 retweets 0 likes
        3. Health Nerd‏Verified account @GidMK 8 Dec 2020
          Replying to @LoneStarLivin

          They report that there are no safety concerns in this subgroup but no specific data in the file that I can seepic.twitter.com/n8WZ4Xa4vq

          1 reply 0 retweets 2 likes
        4. Show replies
        1. bitter_immunologist‏ @BImmunologist 8 Dec 2020
          Replying to @GidMK

          There are reports of some cross reactivity with other corona virus antigens. Some have tried to make the case it leads to less severe COVID, although I haven't actually analyzed the data.

          0 replies 0 retweets 1 like
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        2. Ben Magelsen  🇺🇸‏ @benmagelsen 8 Dec 2020
          Replying to @GidMK

          I have thought reinfection would be rare, but now I'm not so sure. Could be coincidence, but have friend where 2 family members were reinfected in November after all had March infections. The two more sick in March did not reinfect and second infections were closer to colds.🤷‍♂️

          1 reply 0 retweets 1 like
        3. Ketan Kurtadikar‏ @KurtadikarKetan 9 Dec 2020
          Replying to @benmagelsen @GidMK

          Second episode milder in everyone?

          1 reply 0 retweets 1 like
        4. Show replies
        1. Alan‏ @BigAlxyz 8 Dec 2020
          Replying to @GidMK

          Do you have any thoughts on the confusing Astra-Zeneca numbers (accidental half sized first dose leading to much better apparent effectiveness)?

          0 replies 0 retweets 0 likes
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        2. A Marm Kilpatrick‏ @DiseaseEcology 8 Dec 2020
          Replying to @GidMK

          It seems like one would want to see the case accumulation curves to assess this. If most cases weren't already present pre-symptomatically at enrollment, wouldn't it indicate that previous infection provided no protection from symptomatic COVID-19?

          4 replies 0 retweets 1 like
        3. Health Nerd‏Verified account @GidMK 8 Dec 2020
          Replying to @DiseaseEcology

          That's an interesting question. From a study design point of view, it's a selected subgroup so hard to interpret, and it could potentially also be due to their case definition? If someone was recently infected but still PCR positive?

          1 reply 0 retweets 1 like
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        2. Joël Mossong‏Verified account @joel_mossong 8 Dec 2020
          Replying to @GidMK

          But wait, according to the 'reinfections-are-rare' proponents, can only count reinfections were genomes between first and second infection are different.

          1 reply 0 retweets 0 likes
        3. Sam O'Riil‏ @Semoriil 9 Dec 2020
          Replying to @joel_mossong @GidMK

          Is here any mechanism for this virus to stay dormant or something like that to re-emerge later? Otherwise requirement to have different genomes is overkill.

          0 replies 0 retweets 0 likes
        4. End of conversation

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