For those who are interested, the largest clinical trial to date has thus far not shown a benefit for vitamin D supplementation to treat severe COVID-19https://www.medrxiv.org/content/10.1101/2020.11.16.20232397v1 …
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Main results are here - no benefit from vitamin D for hospital stay duration, death, ICU likelihood, or duration of mechanical ventilation Pretty much no impact whatsoeverpic.twitter.com/ERGXKl2TCf
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When Bonferroni would be more appropriate then? And what alternatives would be better here
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The challenge with Bonferroni in this sort of trial is that it eliminates most type 1 errors but increases the possibility of type 2 errors - if the benefit was small, you might miss it. You could use another method i.e. Benjamini-Hochberg
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