This is actually an excellent point that is not made often enough. Most vaccine trials are done over years, so they have smaller numbers because more people get infected. The COVID-19 trials are VASThttps://twitter.com/dfreedman7/status/1331699376419459072 …
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The real worry is chronic diseases that take years to be diagnosed, but that's not the same as serious chronic issues that start immediately after vaccination (which is what people often worry about)
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And this sort of problem tends to be incredibly rare in terms of vaccines. I actually can't think off the top of my head of an example, although I'm sure they exist. Anyone?
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I'm honestly v curious about whether the Oxford/AZN team will address previously raised concerns re. adenovirus vector vaccines and possible increased risk of HIV infection, given that that vaccine might be the first one to see widespread deployment in areas where HIV is endemic.
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Has there ever been a documented “long term” chronic disease from a vaccination?
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