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GidMK's profile
Health Nerd
Health Nerd
Health Nerd
Verified account
@GidMK

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Health NerdVerified account

@GidMK

Epidemiologist. Writer (Guardian, Observer etc). "Well known research trouble-maker". PhDing at @UoW Host of @senscipod Email gidmk.healthnerd@gmail.com he/him

Sydney, New South Wales
theguardian.com/profile/gideon…
Joined November 2015

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    1. Andreas Backhaus‏ @AndreasShrugged 20 Nov 2020

      🍋Quick thread on a new #VitaminD study published in @nature @SciReports. Baseline: High share of severe COVID-19 cases in a hospital in India are Vitamin D deficient. Having that said, I'm not sure if the study is telling us anything new. https://www.nature.com/articles/s41598-020-77093-z … (1/n)

      9 replies 25 retweets 60 likes
      Show this thread
    2. Andreas Backhaus‏ @AndreasShrugged 20 Nov 2020

      The study differentiates between two groups admitted to hospital due to COVID-19: asymptomatic patients (group A) and patients requiring admission to ICU (group B). It measures the patients' Vitamin D levels and monitors the course of their disease. (2/n)

      1 reply 3 retweets 14 likes
      Show this thread
    3. Andreas Backhaus‏ @AndreasShrugged 20 Nov 2020

      In the mild group A, 31.86% were Vitamin D deficient, in the severe group B, 96.82% were Vitamin D deficient. This significant difference partly translated into higher inflammatory markers for group B. Group B also had a much higher fatality rate than group A. (3/n)

      2 replies 3 retweets 19 likes
      Show this thread
    4. Andreas Backhaus‏ @AndreasShrugged 20 Nov 2020

      Now the important stuff: Does the study establish any causal relationship? No. First of all, the groups weren't similar upon admission. The average age of group A was 11 years lower than that of group B. Also comorbidities weren't balanced across the groups. So there were.. (4/n)

      1 reply 3 retweets 20 likes
      Show this thread
    5. Andreas Backhaus‏ @AndreasShrugged 20 Nov 2020

      ...many other potential factors that would be correlated with both the Vitamin D deficit and the higher fatality in group B compared to group A. Second, Vitamin D wasn't administered as part of the study, so it says nothing about the short-run effects of boosting Vitamin D. (5/n)

      2 replies 1 retweet 17 likes
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    6. Andreas Backhaus‏ @AndreasShrugged 20 Nov 2020

      My takeaway from the study is that a Vitamin D deficit is an indicator of poor health, and that poor health increases the likelihood of a severe course of COVID-19 - which we totally knew already. But the means of fixing your health aren't (only) fixing your Vitamin D. (6/n)

      38 replies 81 retweets 545 likes
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    7. Andreas Backhaus‏ @AndreasShrugged 20 Nov 2020

      I'm surprised that the authors "recommend mass administration of vitamin D supplements to population at risk for COVID-19" based on their results or rather on the absence of such. It probably wouldn't do harm, but there's no evidence it would do good regarding COVID-19. (7/n)

      18 replies 6 retweets 44 likes
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    8. Andreas Backhaus‏ @AndreasShrugged 20 Nov 2020

      .@GidMK Feel invited to weigh in.

      2 replies 1 retweet 8 likes
      Show this thread
      Health Nerd‏Verified account @GidMK 20 Nov 2020
      Replying to @AndreasShrugged

      Looks like you've covered it lol. Another terrible vitamin D study

      4:01 PM - 20 Nov 2020
      • 4 Likes
      • 💉 Tom Hansen - social distancing now 😷 Corax The Raven Gert van Dijk ⭕📡 Andreas Backhaus
      1 reply 0 retweets 4 likes
        1. New conversation
        2. Andreas Backhaus‏ @AndreasShrugged 20 Nov 2020
          Replying to @GidMK

          I'm never quite sure whether researchers don't realize that even if they have nothing to say, people will still interpret them as saying something, or whether they're intentionally hoping for this to happen to milk some nothing result to the max.

          1 reply 0 retweets 2 likes
        3. Health Nerd‏Verified account @GidMK 20 Nov 2020
          Replying to @AndreasShrugged

          I think it's often a combination of the two tbh

          0 replies 0 retweets 0 likes
        4. End of conversation

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