A very good thread on that Danish mask paper
https://twitter.com/trishgreenhalgh/status/1329163949732933633 …
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Replying to @MackayIM
Not sure I agree with the "too short" point - they tested IgM as well as IgG and from my understanding that should be detectable much earlier than 2 weeks? Also included PCR+ in their main analysis
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Replying to @GidMK
No baseline PCR test from what I could interpret. Only a self-collected swab at the end of a month. About 7-10d for IgM to peak. IgG can sometimes precede, sometimes accompany appearance of IgM
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Replying to @MackayIM
Sure, but if you had a 30-day PCR, IgG and IgM surely you wouldn't expect to have missed many cases?
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I mean, there's some possibility that none of these tests would pick up someone who got infected right at the end of the study period, but surely you'd expect it to get most of them?
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Actually, I'm thinking carefully about this and I don't think it matters. The study is randomized, so as long as they met their recruitment target and expected power the argument about it being too short makes no sense imo
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