Interesting new preprint on #LongCovid. Some take-homes:
- ~14% of people
- can last months
- associated with +symptoms, previous respiratory disease, gender, age
- not associated with metabolic disease (mostly)https://www.medrxiv.org/content/10.1101/2020.10.19.20214494v1 …
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To me, this is the most interesting table. You can look through and see what is and isn't associated with PCR-positive Long COVIDpic.twitter.com/8VsU8UHz7U
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Not unsurprising that people who experience worse symptoms in their initial COVID-19 infection are more likely to suffer from
#LongCovid1 reply 1 retweet 5 likesShow this thread -
However, some MAJOR limitations to the analysis. The patient group is very selected (people who use and KEEP using an app long term), and this only captures those who had PCR-positive cases of COVID-19
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So, interesting, but I'd be very cautious about drawing inferences from this (i.e. you can't say that 2% of people who get COVID-19 will still have symptoms months later, we don't know if that's true from this study)
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A good way of thinking about it is, I reckon, to say that
#LongCovid does appear to impact a reasonable fraction of people, but exactly who they are is still up in the air and requires much more research1 reply 3 retweets 17 likesShow this thread -
It's also worth noting that we still don't know how much COVID-19 differs from other respiratory diseases in this context, although this study does seem to indicate that those who tested positive for COVID-19 were more likely to experience long-lasting symptomspic.twitter.com/5w3lgCwpag
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Also, I should note that the fact that this data was gathered through an app is definitely an issue. I've actually published research on attrition in app-based interventions, it's a tricky subject https://www.jmir.org/2020/9/e20283/
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Replying to @GidMK
By how much do you think this under-estimates the >12 weeks group?
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Hard to say how much or even if it does tbh, can't readily discern the direction it magnitude of the bias
In other words, 
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Replying to @GidMK
Ok, good to know that we don't know (yet). This one seems to suggest Long Covid is much more persistent? https://www.medrxiv.org/content/10.1101/2020.10.14.20212555v1 … Anyway get ready for "Long Covid is a MYTH 98% have NOTHING"...
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