In an RCT of 1,500 healthcare workers
"Pre-exposure prophylaxis with hydroxychloroquine once or twice weekly did not significantly reduce laboratory-confirmed Covid-19"

HCQhttps://twitter.com/Lauren_J_MacK/status/1317879423190757376 …
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That being said, I think we can safely say that it is increasingly unlikely that HCQ has a benefit COVID-19 prophylaxis, although it is still a possibility that we cannot entirely exclude
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