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GidMK's profile
Health Nerd
Health Nerd
Health Nerd
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@GidMK

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Health NerdVerified account

@GidMK

Epidemiologist. Writer (Guardian, Observer etc). "Well known research trouble-maker". PhDing at @UoW Host of @senscipod Email gidmk.healthnerd@gmail.com he/him

Sydney, New South Wales
theguardian.com/profile/gideon…
Joined November 2015

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    Health Nerd‏Verified account @GidMK 18 Oct 2020

    Health Nerd Retweeted Lauren MacKenzie MD MPH

    In an RCT of 1,500 healthcare workers "Pre-exposure prophylaxis with hydroxychloroquine once or twice weekly did not significantly reduce laboratory-confirmed Covid-19" 💅⚰ HCQhttps://twitter.com/Lauren_J_MacK/status/1317879423190757376 …

    Health Nerd added,

    Lauren MacKenzie MD MPHVerified account @Lauren_J_MacK
    🔥Hot off the peer-reviewed press Hydroxychloroquine as PrEP (Pre-Exposure Prophylaxis) for COVID-19 in healthcare workers: a randomized trial, published in CID https://academic.oup.com/cid/advance-article/doi/10.1093/cid/ciaa1571/5929230 … pic.twitter.com/zNqjcg1wcJ
    Show this thread
    12:42 PM - 18 Oct 2020
    • 23 Retweets
    • 92 Likes
    • Carolina Vázquez blah s‘Steffche *casts Glibness* Michael K. Goode, 🦆 Moi Robin-Ann #GetVaccinated Klotsky, PhD Theonewhoknows flabbergasted
    12 replies 23 retweets 92 likes
      1. New conversation
      2. Health Nerd‏Verified account @GidMK 19 Oct 2020

        To be fair, probably not a nail in the coffin per se. The study didn't have enough infections in the population to be sure that HCQ didn't work, and the confidence interval includes both a large benefit and a large detriment

        1 reply 2 retweets 16 likes
        Show this thread
      3. Health Nerd‏Verified account @GidMK 19 Oct 2020

        That being said, I think we can safely say that it is increasingly unlikely that HCQ has a benefit COVID-19 prophylaxis, although it is still a possibility that we cannot entirely exclude

        4 replies 0 retweets 31 likes
        Show this thread
      4. End of conversation
      1. New conversation
      2. Greg Dore‏ @GregDore2 18 Oct 2020
        Replying to @GidMK

        But, a touch of zinc, a dollop of vit D, a stir & it would be miraculous.

        2 replies 0 retweets 16 likes
      3. Health Nerd‏Verified account @GidMK 18 Oct 2020
        Replying to @GregDore2

        pic.twitter.com/gnV3wHFkxf

        0 replies 0 retweets 3 likes
      4. End of conversation
      1. New conversation
      2. Lars Mølgaard Saxhaug‏ @load_dependent 18 Oct 2020
        Replying to @GidMK

        Rather wide range of possible effect sizes, this does not rule out a clinically meaningful effect, no burial of HCQ based on this as I see it (but I'm very sceptical in any case).pic.twitter.com/46csgk9vfx

        1 reply 1 retweet 4 likes
      3. Health Nerd‏Verified account @GidMK 18 Oct 2020
        Replying to @load_dependent

        Yes, it's true to say that there may be a small benefit not found in this study (despite the impressive size, the prevalence of COVID-19 in the final results was less than they had predicted, so their sample size was not quite adequate)

        0 replies 1 retweet 1 like
      4. End of conversation
      1. This Tweet is unavailable.
      2. Igor Eckert‏ @igoreckert1 19 Oct 2020
        Replying to @camstreet1 @GidMK

        Unfortunately, you don't seem to have read the purpose of the study. "to evaluate whether hydroxychloroquine could prevent Covid-19 in high-risk healthcare workers" Incidence of COVID-19 is the primary endpoint, not "severity of disease".

        0 replies 0 retweets 0 likes
      3. Show replies
      1. Dr Lea Merone MBChB (hons) MPH&TM MSc FAFPHM Ⓥ‏ @LeaMerone 18 Oct 2020
        Replying to @GidMK

        https://onlinelibrary.wiley.com/doi/full/10.1111/1753-6405.13044 … hcq for covid needs putting to bed.

        0 replies 1 retweet 3 likes
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      1. Samir Kayande‏ @SamirKayande 18 Oct 2020
        Replying to @GidMK

        Sweet mother of God what heroes signed up for this?

        0 replies 0 retweets 0 likes
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